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基于随机对照试验真武汤治疗老年慢性心力衰竭临床疗效的Meta分析

赵博雅 王耀健 郭亚鑫 陈露莹 谭颖子 蒋跃绒

国际老年医学杂志2026,Vol.47Issue(3):315-323,9.
国际老年医学杂志2026,Vol.47Issue(3):315-323,9.DOI:10.3969/j.issn.1674-7593.2026.03.009

基于随机对照试验真武汤治疗老年慢性心力衰竭临床疗效的Meta分析

Meta-analysis of the clinical efficacy of Zhenwu decoction in treating chronic heart failure in the elderly based on randomized controlled trials

赵博雅 1王耀健 1郭亚鑫 1陈露莹 1谭颖子 2蒋跃绒1

作者信息

  • 1. 国家中医心血管病临床医学研究中心 中医证候全国重点实验室 中国中医科学院西苑医院心血管中心,北京 100091
  • 2. 北京中医药大学研究生院,北京 100029
  • 折叠

摘要

Abstract

Objective A meta-analysis-based investigation into the clinical efficacy and safety of Zhenwu Decoction in trea-ting chronic heart failure in the elderly.Methods The system searches Chinese and English databases such as CNKI,China Biomed-ical Literature Service System,Wanfang,Chinese Medical Journals Network,China Clinical Trial Registry,International Traditional Medicine Clinical Trial Registration Platform,CSTJ,the Cochrane Library,Embase,PubMed,and Web of Science,with data collec-tion up to November 2025,to include randomized controlled trials on the treatment of chronic heart failure in the elderly with Zhenwu Decoction.Meta-analysis of the data was conducted using RevMan 5.4 and Stata 18.0 software.Results 17 randomized controlled clinical studies were included with a total sample size of 1 782 patients,with 891 patients in the experimental group and 891 patients in the control group.The meta-analysis results showed statistically significant differences between the two groups of patients in terms of clinical efficacy,TCM syndrome scores,left ventricular ejection fraction,left ventricular end-diastolic diameter,left ventricular end-systolic diameter,N-terminal pro-B-type natriuretic peptide,and incidence of adverse reactions(P<0.05).Conclusion Zhenwu Decoction has definite clinical efficacy and good safety in treating elderly chronic heart failure,reducing the incidence of adverse reac-tions.

关键词

随机对照试验/真武汤/老年慢性心力衰竭/Meta分析

Key words

Randomized controlled trials/Zhenwu decoction/Elderly chronic heart failure/Meta-analysis

引用本文复制引用

赵博雅,王耀健,郭亚鑫,陈露莹,谭颖子,蒋跃绒..基于随机对照试验真武汤治疗老年慢性心力衰竭临床疗效的Meta分析[J].国际老年医学杂志,2026,47(3):315-323,9.

基金项目

国家中医药管理局第五批全国中医临床优秀人才研修项目(国中医药人教函[2022]1号) (国中医药人教函[2022]1号)

中国中医科学院西苑医院能力提升项目(XYZX0101-14) (XYZX0101-14)

国际老年医学杂志

1674-7593

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