国际老年医学杂志2026,Vol.47Issue(3):315-323,9.DOI:10.3969/j.issn.1674-7593.2026.03.009
基于随机对照试验真武汤治疗老年慢性心力衰竭临床疗效的Meta分析
Meta-analysis of the clinical efficacy of Zhenwu decoction in treating chronic heart failure in the elderly based on randomized controlled trials
摘要
Abstract
Objective A meta-analysis-based investigation into the clinical efficacy and safety of Zhenwu Decoction in trea-ting chronic heart failure in the elderly.Methods The system searches Chinese and English databases such as CNKI,China Biomed-ical Literature Service System,Wanfang,Chinese Medical Journals Network,China Clinical Trial Registry,International Traditional Medicine Clinical Trial Registration Platform,CSTJ,the Cochrane Library,Embase,PubMed,and Web of Science,with data collec-tion up to November 2025,to include randomized controlled trials on the treatment of chronic heart failure in the elderly with Zhenwu Decoction.Meta-analysis of the data was conducted using RevMan 5.4 and Stata 18.0 software.Results 17 randomized controlled clinical studies were included with a total sample size of 1 782 patients,with 891 patients in the experimental group and 891 patients in the control group.The meta-analysis results showed statistically significant differences between the two groups of patients in terms of clinical efficacy,TCM syndrome scores,left ventricular ejection fraction,left ventricular end-diastolic diameter,left ventricular end-systolic diameter,N-terminal pro-B-type natriuretic peptide,and incidence of adverse reactions(P<0.05).Conclusion Zhenwu Decoction has definite clinical efficacy and good safety in treating elderly chronic heart failure,reducing the incidence of adverse reac-tions.关键词
随机对照试验/真武汤/老年慢性心力衰竭/Meta分析Key words
Randomized controlled trials/Zhenwu decoction/Elderly chronic heart failure/Meta-analysis引用本文复制引用
赵博雅,王耀健,郭亚鑫,陈露莹,谭颖子,蒋跃绒..基于随机对照试验真武汤治疗老年慢性心力衰竭临床疗效的Meta分析[J].国际老年医学杂志,2026,47(3):315-323,9.基金项目
国家中医药管理局第五批全国中医临床优秀人才研修项目(国中医药人教函[2022]1号) (国中医药人教函[2022]1号)
中国中医科学院西苑医院能力提升项目(XYZX0101-14) (XYZX0101-14)