国际神经病学神经外科学杂志2026，Vol.53Issue(2)：41-45,5.DOI:10.16636/j.cnki.jinn.1673-2642.2026.02.006
阿尔茨海默病患者首发精神行为症状分析及影响因素
Analysis of initial behavioral and psychological symptoms of dementia in patients with Alzheimer disease and their influencing factors
摘要
Abstract
Objective To investigate the occurrence of the initial behavioral and psychological symptoms of dementia(BPSD)and their demographic influencing factors in patients with Alzheimer disease(AD).Methods A total of 517 patients with AD who visited the Memory Clinic of The Fourth People's Hospital of Chengdu between January 2021 and October 2024 were included.Data were collected using self-designed questionnaires and scales,followed by statistical analysis.Results Among the initial BPSD in AD patients,delusions were the most common(48.16%),followed by emotional disorders(43.52%),behavioral disorders(28.82%),and hallucinations(23.60%).Of the patients,37.72%presented with more than one initial BPSD.Male patients with AD had a relatively low proportion of initial delusions and a relatively high proportion of initial behavioral disorders(P<0.05),while patients with a spouse had a relatively low proportion of initial delusions(P<0.05).Multivariate logistic regression analysis showed that male sex might be a protective factor for initial delusions,illiteracy and absence of a spouse might be protective factors for emotional disorders,and male sex and illiteracy might be risk factors for behavioral disorders.Conclusions Delusions are the most common initial BPSD in patients with AD,and demographic factors have independent effects on the type of initial BPSD.These findings suggest that,during early assessment of AD,attention should be paid to the characteristics of initial BPSD in different populations,so as to provide a foundation for early identification and personalized intervention.关键词
阿尔茨海默病/精神行为症状/妄想/情绪障碍/行为障碍/幻觉Key words
Alzheimer disease/behavioral and psychological symptoms of dementia/delusion/emotional disorder/behavioral disorder/hallucination分类
医药卫生引用本文复制引用
刘筱薇,万姝,樊薇,韩媛媛,顾锐,徐莉丝,蔡清艳..阿尔茨海默病患者首发精神行为症状分析及影响因素[J].国际神经病学神经外科学杂志,2026,53(2):41-45,5.基金项目
成都市医学科研课题(2023635). （2023635）
