国际神经病学神经外科学杂志2026，Vol.53Issue(2)：62-68,7.DOI:10.16636/j.cnki.jinn.1673-2642.2026.02.008
创伤性脑损伤的动物模型研究进展
Research advances in animal models of traumatic brain injury
裴洁 1徐东刚1
作者信息
- 1. 安徽医科大学,安徽 合肥 230032||军事认知与脑科学研究所,北京 100850
- 折叠
摘要
Abstract
Traumatic brain injury(TBI)is one of the main causes of death and disability worldwide.Current treatment outcomes remain unsatisfactory,and precise diagnosis and effective treatment remain major challenges.TBI has complex causes,pathological changes,and pathogenic mechanisms,and animal models are an effective way to study TBI by simulating disease development and progression,while it is crucial to select appropriate pathological animal models.Various animal models have been used in the past to simulate the development and progression of human TBI,and different TBI animal models have their own characteristics,among which rodents are the most widely used animal model.This article focuses on several commonly used murine animal models for TBI and reviews the establishment,optimization,and application of these models in recent years,in order to provide a reference for research on the mechanism and new treatment strategies for TBI.关键词
创伤性脑损伤/动物模型/鼠/建模方法Key words
traumatic brain injury/animal model/murine/molding method分类
医药卫生引用本文复制引用
裴洁,徐东刚..创伤性脑损伤的动物模型研究进展[J].国际神经病学神经外科学杂志,2026,53(2):62-68,7.
