神经损伤与功能重建2026,Vol.21Issue(5):271-277,7.DOI:10.16780/j.cnki.sjssgncj.20240241
MicroRNA-122在脑血管疾病中的作用及机制研究进展
Research Progress on the Role and Mechanism of MicroRNA-122 in Cerebrovascular Diseases
摘要
Abstract
MicroRNAs are tiny RNAs widely expressed in eukaryotic organisms,exhibiting differential expression in numerous diseases.MicroRNA-122(miR-122)is a signaling molecule closely associated with neurological diseases and has been extensively studied in cerebrovascular diseases.This article provides a review of the role and mechanisms of miR-122 in cerebrovascular diseases,aiming to offer new research targets for cerebrovascular diseases and a theoretical basis for the development of related drugs.关键词
MicroRNA-122/神经系统/脑血管疾病/机制/药物Key words
MicroRNA-122/nervous system/cerebrovascular diseases/mechanism/drugs分类
医药卫生引用本文复制引用
余远芳,吕波..MicroRNA-122在脑血管疾病中的作用及机制研究进展[J].神经损伤与功能重建,2026,21(5):271-277,7.基金项目
广东省自然基金面上项目(Micro RNA-122 调控VCAM-1/NOS2发挥脑保护作用的研究,No.2021A1515012466) (Micro RNA-122 调控VCAM-1/NOS2发挥脑保护作用的研究,No.2021A1515012466)
广东省人民医院2021国自然配套启动基金(MicroRNA-122通过下调NOS2在缺血缺氧性脑损伤后产生脑保护作用的机制研究,No.8217080650) (MicroRNA-122通过下调NOS2在缺血缺氧性脑损伤后产生脑保护作用的机制研究,No.8217080650)