工业微生物2026，Vol.56Issue(2)：1-3,3.DOI:10.3969/j.issn.1001-6678.2026.02.001
藏红花素的微生物合成研究进展
Research Progress in Microbial Synthesis of Crocins
肖亚倩 1刘玲童 1乔立琛 1杨建 1梁珈浩 1王军1
作者信息
- 1. 湖北工业大学工业发酵省部共建协同创新中心,武汉 430068||湖北工业大学生命科学与健康工程学院,武汉 430068
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摘要
Abstract
Crocins are a class of water-soluble carotenoids,and exhibit pharmacological activities such as anti-tumor,anti-inflammatory,anti-oxidative stree,and neuroprotective effects,demonstrating broad application prospects.However,their traditional plant extraction methods suffer from low yields and high costs,which limits its application.In recent years,microbial heterologous synthesis has emerged as a research hotspot owing to its short production cycle,low cost,and genetic manipulability.This paper summarizes the structural characteristics,pharmacological activities,and advances in microbial synthesis of crocins,with a focus on engineering strategies utilizing Escherichia coli and Saccharomyces cerevisiae.Future efforts should emphasize enzyme functional exploration and metabolic regulation of crocins to facilitate their application in pharmaceutical and food industries.关键词
藏红花素/微生物合成/代谢工程/大肠杆菌/酿酒酵母Key words
crocins/microbial synthesis/metabolic engineering/Escherichia coli/Saccharomyces cerevisiae引用本文复制引用
肖亚倩,刘玲童,乔立琛,杨建,梁珈浩,王军..藏红花素的微生物合成研究进展[J].工业微生物,2026,56(2):1-3,3.
