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ALT/ALP、ALP/GGT与妊娠期肝内胆汁淤积症的相关性研究

崔亚会 张润学 贾璐瑶 刘玉

工业微生物2026,Vol.56Issue(2):17-19,3.
工业微生物2026,Vol.56Issue(2):17-19,3.DOI:10.3969/j.issn.1001-6678.2026.02.006

ALT/ALP、ALP/GGT与妊娠期肝内胆汁淤积症的相关性研究

Study on the Correlation between ALT/ALP,ALP/GGT and Intrahepatic Cholestasis of Pregnancy

崔亚会 1张润学 2贾璐瑶 1刘玉2

作者信息

  • 1. 河北北方学院,张家口 075132||河北省人民医院,石家庄 050051
  • 2. 河北省人民医院,石家庄 050051
  • 折叠

摘要

Abstract

Intrahepatic cholestasis of pregnancy(ICP)is a major pregnancy complication threatening the safety of perinatal.This study investigated the correlation between alanine aminotransferase/alkaline phosphatase(ALT/ALP),alkaline phosphatase/γ-glutamyl transferase(ALP/GGT),and ICP.Comparative analysis of biochemical indicators between the ICP group and the healthy pregnant women group revealed that the ALT/ALP and ALP/GGT ratios showed statistically significant differences between the ICP group and the control group(P<0.05).The combined prediction of ICP using TBA,GGT,and ALP/GGT yielded an area under the curve(AUC)of 0.993,superior to the predictive value of individual and other combined indicators.

关键词

妊娠期肝内胆汁淤积症/丙氨酸转氨酶/碱性磷酸酶/γ-谷氨酰胺转移酶

Key words

intrahepatic cholestasis of pregnancy/alanine aminotransferase/alkaline phosphatase/γ-glutamyl transferase

引用本文复制引用

崔亚会,张润学,贾璐瑶,刘玉..ALT/ALP、ALP/GGT与妊娠期肝内胆汁淤积症的相关性研究[J].工业微生物,2026,56(2):17-19,3.

工业微生物

1001-6678

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