湖南中医药大学学报2026，Vol.46Issue(3)：651-656,6.DOI:10.3969/j.issn.1674-070X.2026.03.030
基于MAPK信号通路探讨中医药治疗肺癌的研究进展
Research progress in treating lung cancer with TCM based on the MAPK signaling pathway
摘要
Abstract
This article systematically explores the mechanism of action of the MAPK signaling pathway in regulating cell proliferation and apoptosis,invasion and metastasis,immunity,reversal of drug resistance,and regulation of the cell cycle.Additionally,it reviews the research progress on anti-lung cancer effects mediated by the modulation of the MAPK signaling pathway through active components of TCM,including flavonoids,saponins,and alkaloids,as well as TCM compound formulas such as Yiqi Fuzheng Formula,Yangfei Formula,and Feiyanning Granules.The aim is to provide a theoretical foundation for the development of clinical anti-lung cancer drugs.关键词
肺癌/MAPK信号通路/中药活性成分/中药复方/分子机制Key words
lung cancer/MAPK signaling pathway/active components of TCM/TCM compound formulas/molecular mechanism分类
医药卫生引用本文复制引用
耿晨曦,谷冰冰,孟泳..基于MAPK信号通路探讨中医药治疗肺癌的研究进展[J].湖南中医药大学学报,2026,46(3):651-656,6.基金项目
国家科技重大专项(2024ZD0522902) （2024ZD0522902）
河南省高等学校重点科研项目计划(24A360011) （24A360011）
河南省中医药科学研究专项课题(2023ZY3008). （2023ZY3008）
