吉林中医药2026，Vol.46Issue(5)：552-556,5.DOI:10.13463/j.cnki.jlzyy.2026.05.004
基于"脾虚浊毒"理论探析慢性萎缩性胃炎"炎-癌转化"机制与防治策略
Analysis of the pathogeneses and prevention and treatment strategies of the"inflammation-cancer transformation"in chronic atrophic gastritis based on the theory of"spleen deficiency and turbidity"
摘要
Abstract
Chronic atrophic gastritis(CAG)is one of the common clinical diseases and is also a key stage of"inflammation-cancer transformation".The process mainly involves multiple pathogeneses such as persistent inflammatory response,imbalance of gastric mucosal microenvironment and abnormal cell proliferation."Spleen deficiency and turbidity",first proposed by Li Diangui,a master of traditional Chinese medicine,is believed by more and more researchers to be the core pathogenesis of CAG,in which spleen deficiency constitutes its root cause while turbidity its manifestation,and the two influence each other to induce the disease,promoting its evolution from"inflammation"to"cancer".Based on the classic theory of"spleen deficiency and turbidity"and combined with modern research results,this article systematically explains the pathogeneses of CAG"inflammation-cancer transformation",and proposes its intervention strategies from the perspective of staged syndrome differentiation and treatment,in order to provide a theoretical basis and clinical reference for the TCM prevention and control of the early evolution of gastric cancer.关键词
脾虚浊毒/慢性萎缩性胃炎/炎-癌转化/病机演变/中医防治Key words
spleen deficiency and turbidity/chronic atrophic gastritis/inflammation-cancer transformation/pathogenesis evolution/TCM prevention and treatment分类
医药卫生引用本文复制引用
陈萌,刘洁,吴胜兰,汤慧君,秦先锋,别彩群..基于"脾虚浊毒"理论探析慢性萎缩性胃炎"炎-癌转化"机制与防治策略[J].吉林中医药,2026,46(5):552-556,5.基金项目
国家自然科学基金青年科学基金项目(82305236) （82305236）
广东省中医药局科研项目(202405112001157150) （202405112001157150）
