实用临床医药杂志2026，Vol.30Issue(7)：48-53,6.DOI:10.7619/jcmp.20256930
改良全视网膜激光光凝术治疗白内障合并重度非增殖期糖尿病视网膜病变患者的临床效果
Clinical efficacy of modified panretinal photocoagulation in treating patients with cataract complicated by severe non-proliferative diabetic retinopathy
摘要
Abstract
Objective To investigate the efficacy and safety of modified panretinal photocoagula-tion in treating patients with cataract complicated by severe non-proliferative diabetic retinopathy(sNPDR).Methods A total of 130 patients with cataract complicated by sNPDR were selected as the study subjects.Using a random number table method,the patients were divided into modified group(n=65)and control group(n=65).The modified group underwent modified panretinal photo-coagulation,while the control group received conventional panretinal photocoagulation.General data of patients in both groups were collected.Comparisons were made between the two groups regarding central foveal thickness(CFT),best-corrected visual acuity(BCVA),area of retinal non-perfusion(ARN),intraocular pressure(IOP)and the occurrence of complications.Results At 1-,3-and 6-month postoperatively,the BCVA(LogMAR)of both groups was lower than that before the operation;the CFT and BCVA(LogMAR)of the modified group were lower than those of the control group,and the difference was statistically significant(P＜0.05).At 1-,3-and 6-month postoperatively,the ARN in both groups was significantly smaller than that preoperatively,and the value in the modified group was significantly smaller than that in the control group(P＜0.05).At 1-,3-and 6-month postoper-atively,the fluctuation range of IOP in the modified group was significantly smaller than that in the control group(P＜0.05).The overall complication rate in the modified group was 15.38％,which was significantly lower than 30.77％in the control group(x2=4.333,P=0.037).Conclusion Modified panretinal photocoagulation is superior to conventional panretinal photocoagulation in treating sNPDR complicated by cataract.It can more effectively improve CFT,BCVA,and ARN,reduce IOP fluc-tuations,and offers comparable safety.Thus,it is the preferred option for individualized treatment of such patients.关键词
改良全视网膜激光光凝术/重度非增殖期糖尿病视网膜病变/白内障/眼压/视网膜无灌注区面积/黄斑中心凹视网膜厚度/最佳矫正视力/并发症Key words
modified panretinal photocoagulation/severe non-proliferative diabetic retinopathy/cataract/intraocular pressure/area of retinal non-perfusion/central foveal thickness/best-corrected visual acuity/complications分类
医药卫生引用本文复制引用
朱芙蓉,喻娟,周丽琼,杨冬珍,程惠,陈向东,谭甘露..改良全视网膜激光光凝术治疗白内障合并重度非增殖期糖尿病视网膜病变患者的临床效果[J].实用临床医药杂志,2026,30(7):48-53,6.基金项目
国家自然科学基金面上项目(82374525) （82374525）
