检验医学与临床2026，Vol.23Issue(9)：1172-1176,5.DOI:10.3969/j.issn.1672-9455.2026.09.004
强脉冲光+茶树精油湿巾+睑板腺按摩治疗蠕形螨性睑缘炎的疗效观察
Observation on the efficacy of intense pulsed light+tea tree oil wipes+meibomian gland massage in the treatment of demodex blepharitis
摘要
Abstract
Objective To analyze the clinical efficacy of intense pulsed light(IPL)+tea tree oil(TTO)wipes+meibomian gland massage(MGE)in the treatment of demodex blepharitis.Methods A total of 55 patients(106 eyes)diagnosed with demodex blepharitis in the outpatient department of the hospital from Feb-ruary 2023 to December 2024 were selected as the research subjects.According to the treatment plan received by the patients,they were divided into the control group[MGE+TTO wipes treatment,26 cases(51 eyes)]and the combined treatment group[IPL+MGE+TTO wipes treatment,29 cases(55 eyes)].Before treatment and 8 weeks after treatment,the number of demodex mites,tear film break-up time(TBUT)of the patients were detected,and the Ocular Surface Disease Index(OSDI)score,Meibomian Gland Opening Obstruction score and Meibomian Gland Secretion Quality score of the patients were evaluated.Results After treatment,the OSDI,Meibomian Gland Opening Obstruction score and Meibomian Gland Secretion Quality score of both groups were lower than those before treatment,and those in the combined treatment group were lower than those in the control group,with statistically significant differences(P＜0.05).There was a statistically signif-icant difference in TBUT between the two groups before treatment(P＜0.05).After treatment,the TBUT of both groups was longer than that before treatment,and the TBUT of the combined treatment group was lon-ger than that of the control group,with statistically significant differences(P＜0.05).After treatment,the ΔTBUT of the combined treatment group was higher than that of the control group(P＜0.05).After treat-ment,the number of demodex mites in both groups was less than that before treatment,and that in the com-bined treatment group was less than that the the control group,with statistically significant differences(P＜0.05).Conclusion IPL+TTO wipes+MGE is an efficient comprehensive treatment plan for demodex bleph-aritis.Compared with MGE combined with TTO wipes,this combined mode can improve the clinical symp-toms and ocular surface signs of patients and has important clinical promotion value.关键词
蠕形螨性睑缘炎/强脉冲光/茶树精油/睑板腺功能障碍/物理治疗Key words
demodex blepharitis/intense pulsed light/tea tree oil/meibomian gland dysfunction/physical therapy分类
医药卫生引用本文复制引用
严红,高利霞,杨思思,杨于力..强脉冲光+茶树精油湿巾+睑板腺按摩治疗蠕形螨性睑缘炎的疗效观察[J].检验医学与临床,2026,23(9):1172-1176,5.基金项目
国家自然科学基金面上项目(82271055) （82271055）
重庆市科卫联合医学科研面上项目(2022MSXM051). （2022MSXM051）
