昆虫学报2026，Vol.69Issue(4)：565-580,16.DOI:10.16380/j.kcxb.2026.04.009
番茄斑萎病毒-西花蓟马-植物三者互作的研究进展
Research progresses in the tripartite interactions of tomato spotted wilt orthotospovirus-Frankliniella occidentalis-plants
摘要
Abstract
Tomato spotted wilt orthotospovirus(TSWV)is one of the most destructive plant viruses in the world and continously poses a serious threat to agricultural ecosystems in China.Its epidemiological and pathogenic mechanisms are largely governed by intricate tripartite interactions involving the virus,vectors and plants.In recent years,with the widespread application of molecular biology and multi-omics technologies,a series of significant progress has been made in China in the field of TSWV-Frankliniella occidentalis-plant interactions.In this article,we systematically summarized the key research achievements in China since the beginning of the 21st century in understanding the TSWV-F.occidentalis-plant interaction mechanisms,developing control strategies,and exploring the resource-oriented utilization of the virus.We further provided a forward-looking perspective on integrated viral disease management.Multiple studies have elucidated that various effector proteins encoded by TSWV play key roles in modulating physiological processes in both plants and its insect vector by targeting host proteins,and perturbing their metabolic and defense pathways.In plants,TSWV infection systemically suppresses host defense responses,while plants employ disease resistance proteins to recognize viral components and activate immune responses,thereby establishing effective defense barriers.Within the vector F.occidentalis,TSWV not only replicates and propagates effectively,but also regulates the growth and development,fecundity,and behavioral traits of the vector,ultimately enhancing the viral transmission efficiency.Moreover,TSWV-induced physiological changes in plants can indirectly improve the fitness of the vector insect,collectively forming a complex cross-kingdom tripartite interaction network.Regarding control strategies,based on in-depth understanding of tripartite interaction mechanisms,Chinese researchers have achieved notable advances in compound-mediated antiviral intervention,plant immunity induction,innovation of resistant germplasm,and genetic engineering.Several small-molecule inhibitors targeting virus proteins,natural-source immune inducers,and precisely designed disease-resistant germplasm resources have been developed.Simultaneously,the resource-oriented utilization of TSWV as a biotechnological tool shows considerable potential.Future studies should prioritize elucidating key scientific questions including the dynamic balance between TSWV pathogenicity and host resistance,the fine-tuned mechanisms of viral cross-host transmission and the virus-mediated global effects within ecological networks.It is essential to integrate artificial intelligence,synthetic biology,advanced imaging and multi-omics technologies in a multidisciplinary framework,in order to drive innovation in disease-resistant breeding,enable the intelligent development of novel targeted intervention agents and facilitate the design of ecological regulation strategies.These efforts will ultimately establish a green and sustainable integrated viral disease management system,and open new pathways for the resource-oriented utilization of TSWV as a biotechnology tool.关键词
番茄斑萎病毒/西花蓟马/虫媒病毒/三者互作/宿主防御/防控策略Key words
Tomato spotted wilt orthotospovirus/Frankliniella occidentalis/insect-vectored viruses/tripartite interaction/host defense/control strategies分类
农业科技引用本文复制引用
王宏伟,叶健..番茄斑萎病毒-西花蓟马-植物三者互作的研究进展[J].昆虫学报,2026,69(4):565-580,16.基金项目
国家自然科学基金项目(32125032) （32125032）
中国科学院稳定支持基础研究领域青年团队计划(YSBR-080) （YSBR-080）
