临床与实验病理学杂志2026，Vol.42Issue(4)：426-432,7.DOI:10.13315/j.cnki.cjcep.2026.04.002
2025 ERS/ATS间质性肺炎国际多学科分类的诊断新范式和挑战
The 2025 ERS/ATS international multidisciplinary classification of interstitial pneumonia:diagnostic paradigm and challenges
摘要
Abstract
In 2025,the European Respiratory Society(ERS)and the American Thoracic Society(ATS)jointly released the Update of the International Multidisciplinary Classification of the Interstitial Pneumonias,representing a systematic revision of the classification framework for interstitial pneumonia(IP).A major advancement of this update is the expansion of its scope from idiopathic interstitial pneumonias(IIP)to encompass IP of all etiologies,thereby es-tablishing a unified classification framework.The revised classification formally recognizes bronchiolocentric intersti-tial pneumonia(BIP)as an independent pathological pattern,replaces desquamative interstitial pneumonia(DIP)with the more pathologically appropriate term alveolar macrophage pneumonia(AMP),and substitutes acute intersti-tial pneumonia(AIP)with diffuse alveolar damage(DAD).Based on anatomical localization and disease behavior,the updated system establishes a new framework centered on interstitial diseases(subdivided into fibrotic and non-fibrotic types)and airspace-filling diseases,and introduces a diagnostic confidence stratification system.From patho-logical and radiological perspectives,this article systematically reviews the key elements of this classification update,with particular emphasis on the transition toward a three-dimensional"pattern-etiology-behavior"diagnostic paradigm and its implications for clinical practice.关键词
间质性肺炎/诊断模式/多学科讨论/病理-影像学特征Key words
interstitial pneumonia/diagnostic paradigm/multidisciplinary discussion/pathologic-radiologic features分类
医药卫生引用本文复制引用
邓宇,易祥华,王顺利..2025 ERS/ATS间质性肺炎国际多学科分类的诊断新范式和挑战[J].临床与实验病理学杂志,2026,42(4):426-432,7.基金项目
国家自然科学基金(82170082)、国家重大科技专项(2025ZD0549204)、人卫研究院医学影像与创新发展研究项目(HX25AII001036)、同济大学附属同济医院国自然培育项目(GIPY2406) National Natural Science Foundation of China(82170082) （82170082）
The National Key Research and Devel-opment Program of China(2025ZD0549204) （2025ZD0549204）
The Medical Imaging and Innovation Development Research Project of the People's Medical Publishing House Institute(HX25AII001036) （HX25AII001036）
The Natural Science Foundation Cultivation Project of Tongji Hospital,Tongji University(GIPY2406) （GIPY2406）
