中国临床保健杂志2026，Vol.29Issue(2)：191-194,4.DOI:10.3969/J.issn.1672-6790.2026.02.009
内皮祖细胞在下肢动脉硬化闭塞症治疗中的作用机制及应用前景
Mechanisms and application prospects of endothelial progenitor cells in the treatment of lower extremity arteriosclerosis obliterans
摘要
Abstract
As a common disease in vascular surgery,the incidence of lower extremity arteriosclerosis occlusion(ASO)is increasing with the acceleration of population aging and lifestyle changes.The disease not only has a high rate of restenosis,but is also prone to serious adverse events such as amputation due to limb gangrene,which not only seriously damages the quality of life of patients,but also brings a heavy burden to the clinical diagnosis and treatment system and social and public health resources.Therefore,exploring more efficient and lasting treatment strategies has become a key topic that needs to be solved urgently in clinical practice and scientific research.Endothelial progenitor cells(EPC)have become a hot topic of research in the field of revascularization therapy in recent years due to their ability to repair damaged endothelium,promote angiogenesis,and regulate vascular function.This article focuses on the biological characteristics of EPC and its mechanism in the treatment of ASO,and looks forward to its application prospects in the treatment of ASO.关键词
闭塞性动脉硬化/内皮祖细胞/细胞和组织疗法/再生Key words
Arteriosclerosis obliterans/Endothelial progenitor cells/Cell-and tissue-based therapy/Regeneration引用本文复制引用
王烨,高占峰..内皮祖细胞在下肢动脉硬化闭塞症治疗中的作用机制及应用前景[J].中国临床保健杂志,2026,29(2):191-194,4.基金项目
内蒙古自治区公立医院科研联合基金科技项目(2025GLLH0158) （2025GLLH0158）
内蒙古自治区卫生健康委科研项目(202202162) （202202162）
内蒙古医科大学面上项目(YKD2021MS007) Scientific Research Joint Fund Project of Public Hospitals in Inner Mongolia Autonomous Region(2025GLLH0158) （YKD2021MS007）
Scientific Research Project of the Health Commission of Inner Mongolia Autonomous Region(202202162) （202202162）
General Project of Inner Mongolia Medical University(YKD2021MS007) （YKD2021MS007）
