皮肤性病诊疗学杂志2026，Vol.33Issue(4)：277-283,7.DOI:10.3969/j.issn.1674-8468.2026.04.005
自体乳糜脂肪移植在面部年轻化中的临床应用
Clinical application of autologous chylous fat grafting in facial rejuvenation
摘要
Abstract
Objective To explore the clinical efficacy of autologous chylous fat transplantation in improving facial wrinkles,skin laxity,and enlarged pores in subjects with moderate to severe facial photoaging,as well as to ascertain its clinical applicability and safety.Methods A total of 20 subjects with moderate to severe facial photoaging admitted to our hospital from June 2023 to July 2024 were enrolled,all of whom underwent autologous chylous fat transplantation.Fat was harvested from their thighs or abdomen,purified,and emulsified into chylous fat,which was then precisely injected into the areas with facial wrinkles and enlarged pores.Before surgery and three months after surgery,Glogau's four-grade photoaging classification was used to evaluate the grade of facial wrinkles.An ElastiMeter skin firmness tester was employed to measure skin firmness,while a five-point photographic scale was used to quantitatively assess pore improvement.The oc-currence of postoperative complications was recorded.Results At 3 months after surgery,the av-erage grade of facial wrinkles decreased from 3.52±0.80 preoperatively to 2.03±0.30(t=0.43,P=0.011).Skin firmness increased from 20.34±3.80 to 29.51±5.50(t=0.32,P=0.001),and the average grade of pores reduced from 3.70±1.21 to 2.10±1.01(t=0.65,P=0.012).Postoperatively,there were 1 case of edema and 1 case of fat necrosis,with no serious adverse events observed.Conclusions Autologous chylous fat transplantation can significantly im-prove wrinkles,skin laxity,and enlarged pores caused by facial photoaging.The incidence of postoperative complications was low,indicating that this treatment is safe and effective for the treatment of facial photoaging.关键词
光老化/自体乳糜脂肪移植/自体移植/面部皱纹/皮肤松弛/年轻化Key words
photoaging/autologous chylous fat grafting/autologous transplantation/facial wrinkles/skin laxity/rejuvenation引用本文复制引用
黄吉波,彭琦玲,曹秀容,邹思怡,陈嘉蕾,米颖..自体乳糜脂肪移植在面部年轻化中的临床应用[J].皮肤性病诊疗学杂志,2026,33(4):277-283,7.基金项目
广州市白云区人民医院院长基金(BYYZ24015) （BYYZ24015）
