国际眼科杂志2026，Vol.26Issue(6)：983-989,7.DOI:10.3980/j.issn.1672－5123.2026.6.09
应用UWF－OCTA与视网膜血氧仪评估原发性青光眼患者视网膜血流改变的研究进展
Advances in evaluating retinal blood flow alterations in primary glaucoma patients using UWF－OCTA and retinal oximetry
摘要
Abstract
•Glaucoma is one of the leading causes of blindness worldwide.Elevated intraocular pressure is a major factor contributing to glaucomatous optic neuropathy.However,the complete mechanisms underlying glaucomatous damage remain incompletely understood.In recent years,the emergence of new technologies such as ultra － widefield optical coherence tomography angiography(UWF － OCTA)and retinal oximetry has provided increasing evidence that retinal vascular and hemodynamic factors are closely associated with the pathogenesis of glaucoma.UWF－OCTA primarily detects the movement trajectory of red blood cells in retinal vessels,enabling rapid scanning and reconstruction of the retinal microvascular network,which can be quantified to assess changes in retinal blood perfusion and vascular morphology.Retinal oximetry,utilizing multispectral imaging(MSI)and laser speckle flowgraphy(LSFG),allows non－invasive measurement of parameters such as retinal arterial and venous oxygen saturation,directly reflecting tissue metabolic demand and blood oxygen delivery efficiency.The multimodal complementary approach provides valuable insights for investigating the correlation between retinal and choroidal vascular and hemodynamic factors and glaucomatous damage.This review aims to summarize the basic principles of UWF－ OCTA and retinal oximetry,as well as their current advancements in glaucoma research.关键词
超广角光学相干断层扫描血管成像(UWF－OCTA)/视网膜血氧仪/青光眼/血流密度/血氧饱和度Key words
ultra-widefield optical coherence tomography angiography(UWF-OCTA)/retinal oximetry/glaucoma/vessel density/oxygen saturation引用本文复制引用
赵丹,陈红..应用UWF－OCTA与视网膜血氧仪评估原发性青光眼患者视网膜血流改变的研究进展[J].国际眼科杂志,2026,26(6):983-989,7.基金项目
河北省卫健委重点科技研究计划项目(No.20241585) Key Scientific Research Project of Health Commission of Hebei Province(No.20241585) （No.20241585）
