农业与技术2026，Vol.46Issue(5)：1-6,6.DOI:10.19754/j.nyyjs.20260530001
葛根抗衰老及其相关疾病的研究进展
Research Progress on the Anti-Aging and Anti-Age-Related Disease Effects of Pueraria lobata
摘要
Abstract
As a Medicinal and edible herb in China,Pueraria lobata has s a long history of medicinal and dietary application.Modern pharmacological research identified its bioactive compounds,including isoflavonoids(puerarin,daidzein,and genistein),polysaccharides,proteins,and other constituents.These components demonstrate significant anti-aging pharmacological activities,including anti-inflammatory,antioxidant,autophagy regulation,and improvement of mitochondrial function.This review systematically summarizes the core molecular mechanisms of Pueraria lobata and its active constituents in delaying the aging process and preventing aging-related diseases,particularly in counteracting oxidative stress and inflammatory responses,regulating autophagy,and enhancing mitochondrial function.This review provides an in-depth analysis of the"multi-component-multi-target-multi-pathway"synergistic anti-aging pharmacological effect of Pueraria lobata.Under the circumstance of population aging,this review provides a reference for the application of Pueraria lobata in age-related diseases and the development of anti-aging products.关键词
葛根/活性成分/抗衰老/作用机制/衰老相关疾病Key words
Pueraria lobata/active components/anti-aging/mechanism/age-related disease分类
农业科技引用本文复制引用
李治宽,朱越,高翔,何美军,罗凯,彭诗琴..葛根抗衰老及其相关疾病的研究进展[J].农业与技术,2026,46(5):1-6,6.基金项目
农业农村部现代农业产业技术体系建设专项国家中药材产业技术体系(项目编号:CARS-21) （项目编号:CARS-21）
湖北省农业科学院青年科学基金(项目编号:2024NKYJJ37) （项目编号:2024NKYJJ37）
