中国海洋大学学报（自然科学版）2026，Vol.56Issue(6)：1-15,65,16.DOI:10.16441/j.cnki.hdxb.20250212
神经毒素2,4-二氨基丁酸的来源、分布及致毒机理研究进展与展望
Research Progress on the Source,Distribution and Toxicological Mechanisms of Neurotoxin 2,4-diaminobutyric Acid and Future Prospect
摘要
Abstract
2,4-diaminobutyric acid(DAB)is a neurotoxic non-protein amino acid,which has been widely detected in various biological samples,posing potential threats to aquatic ecosystems and human health.Based on existing domestic and international literature,this paper systematically reviews the de-tection of DAB in bacteria,cyanobacteria,eukaryotic phytoplankton,aquatic animals,and environmen-tal samples,summarizes the main toxicological mechanisms of DAB,and provides an important refer-ence for toxicology and health risk research of DAB.The future research directions related to DAB are prospected based on the current research progress.It is still necessary to further confirm the true bio-logical source of DAB in the algal culture system,reveal the metabolic and enrichment pathways of DAB in organisms,and establish environmental quality benchmarks.关键词
2,4-二氨基丁酸/神经毒素/生物来源/致毒机制Key words
2,4-diaminobutyric acid(DAB)/neurotoxin/biological source/toxicological mechanism分类
资源环境引用本文复制引用
李爱峰,党慧,邱江兵,王桂祥,李敏,闫国旺..神经毒素2,4-二氨基丁酸的来源、分布及致毒机理研究进展与展望[J].中国海洋大学学报（自然科学版）,2026,56(6):1-15,65,16.基金项目
国家自然科学基金山东联合基金重点支持项目(U2106205)资助Supported by the Joint Fund of the National Natural Science Foundation of China and Shandong Province(U2106205) （U2106205）
