老年睡眠障碍的重复经颅磁刺激精准干预专家共识
Expert consensus on precise intervention with repetitive transcranial magnetic stimulation for sleep disorders in the elderly
摘要
Abstract
In recent years,repetitive transcranial magnetic stimulation(rTMS)has garnered significant attention as a therapeutic approach for sleep disorders in the elderly.However,the prevailing rTMS protocols are predominantly developed based on normative neurophysiological data derived from young adults and fail to incorporate individualized parameters tailored to the brain characteristics of the elderly.To address this gap,the consensus development group synthesized the latest evidence from 2010 to 2025 and established a standardized rTMS protocol specifically for elderly patients with sleep disorders.Adhering to the Appraisal of Guidelines for Research and Evaluation II(AGREE II)framework,systematically screened randomized controlled trials(RCTs)and systematic reviews regarding rTMS in the treatment of sleep disorders across various conditions.Meanwhile,the Grading of Recommendations Assessment,Development and Evaluation(GRADE)system was employed to rigorously grade the quality of evidence and the strength of recommendations.This consensus guideline delineates precise rTMS protocols for the management of sleep disorders in the elderly,highlights the adjustment of stimulation intensity according to scalp-cortex distance recommends either MRI-guided neuronavigation or the Beam F3/F4 heuristic approach for accurate target localization,thereby providing precise rTMS intervention protocol for sleep disorders in the elderly,aiming to enhance clinical efficacy while ensuring treatment safety.关键词
老年/睡眠障碍/重复经颅磁刺激/抑郁障碍/轻度认知障碍/阿尔茨海默病Key words
The elderly/Sleep disorders/Repetitive transcranial magnetic stimulation/Depression disorder/Mild cognitive impairment/Alzheimer's disease分类
医药卫生引用本文复制引用
邵园,王永军,王建,梁炜,张迎黎,侯刚强,李霞,邢怡,王露,唐诗..老年睡眠障碍的重复经颅磁刺激精准干预专家共识[J].四川精神卫生,2026,39(2):97-105,9.基金项目
国家重点研发计划(项目名称:衰老过程心理-睡眠-认知相互作用机理及干预研究,项目编号:2023YFC3603200) (项目名称:衰老过程心理-睡眠-认知相互作用机理及干预研究,项目编号:2023YFC3603200)
深圳市科技创新局基础研究面上项目(项目名称:老年睡眠障碍的时空图神经网络(STGNN)机制研究,项目编号:JCYJ20240813112859008 (项目名称:老年睡眠障碍的时空图神经网络(STGNN)
项目名称:生物节律介导的脑类淋巴系统功能紊乱在抑郁症发病机制中的研究,项目编号:JCYJ20240813112900002) ()
市康宁医院院级科研项目-青年项目(项目名称:光生物节律调控在AD治疗中的作用及其机制研究,项目编号:KN2023A004)www.guidelines-registry.cn 注册号:PREPARE-2026CN530 Funded by National Key Research and Development Program(number,2023YFC3603200) (项目名称:光生物节律调控在AD治疗中的作用及其机制研究,项目编号:KN2023A004)
General Program of Shenzhen Science and Technology Innovation Commission(number,JCYJ20240813112859008,JCYJ20240813112900002) (number,JCYJ20240813112859008,JCYJ20240813112900002)
Youth Program of Shenzhen Kangning Hospital(number,KN2023A004) (number,KN2023A004)
www.guidelines-registry.cn number,PREPARE-2026CN530 ()