四川中医2026，Vol.44Issue(5)：53-58,6.DOI:10.26946/j.cnki.1000-3649.sczy.2512020008
滋润霜联合洁尔阴洗液治疗脾肾两虚型女性慢性外阴瘙痒的临床研究
Clinical study on the combined use of Moisturizing cream and Jie'eryin wash for treating chronic vulvar itching in women with spleen-kidney deficiency
摘要
Abstract
Objective To evaluate the clinical efficacy and safety of Moisturizing cream combined with Jie'eryin wash in treating spleen-kidney deficiency type chronic vulvar pruritus(VP)in women.Methods A randomized controlled trial was conducted involving 70 female patients with chronic VP due to spleen-kidney deficiency,who sought treatment between March 2024 and May 2025.Participants were randomly assigned to either the experimental group(topical application of Moisturizing cream combined with Jie'eryin wash)or the control group(topical application of Jie'eryin wash only),each comprising 35 patients.The treatment course lasted one month.Visual analog scale(VAS)scores for pruritus,skin lesion scores,and traditional Chinese medicine(TCM)syndrome scores were assessed before and after treatment.Clinical efficacy rates were evaluated,with 3-month follow-up monitoring for recurrence rates and adverse reactions.Results 68 cases completed the study,with 34 cases in each of the experimental and control groups.Statistically significant differences existed in the distribution of efficacy grades between groups(U=727.000,P=0.032).The total effective rate was higher in the experimental group than in the control group(97.06%vs 85.29%),and the cure rate was also higher in the experimental group(76.47%vs 52.94%).Post-treatment itch scores improved more significantly in the experimental group than the control group(U=414.00,P=0.041).The difference in improvement of skin lesion scores between groups was at the borderline of statistical significance(U=425.500,P=0.05).Improvement in TCM syndrome scores was superior to the control group(U=302.500,P=0.001).The recurrence rate was lower in the experimental group than in the control group(3.85%vs 11.11%,P=0.558),but the difference between groups was not statistically significant.No serious drug-related adverse events occurred in either group.Conclusion The combination of Moisturizing cream and Jie'eryin wash solution significantly improves symptoms of chronic VP in women with spleen-kidney deficiency pattern.It demonstrates reliable efficacy and high safety,warranting clinical promotion and application.关键词
慢性外阴瘙痒/脾肾两虚/滋润霜/洁尔阴洗液/中医外治/随机对照试验Key words
Chronic vulvar pruritus/Spleen-kidney deficiency/Moisturizing cream/Jie'eryin wash/Traditional Chinese medicine external treatment/Randomized controlled trial分类
医药卫生引用本文复制引用
谭卓林,陈淑涛..滋润霜联合洁尔阴洗液治疗脾肾两虚型女性慢性外阴瘙痒的临床研究[J].四川中医,2026,44(5):53-58,6.基金项目
第七批全国老中医药专家(陈淑涛)学术经验继承工作(国中医药人教函[2022]76号) （陈淑涛）
四川省中医药管理局名中医工作室建设项目(2021-01-013-02) （2021-01-013-02）
2023年度四川省中医药管理局科学技术研究专项课题(2023MS181). （2023MS181）
