上海针灸杂志2026，Vol.45Issue(5)：516-521,6.DOI:10.13460/j.issn.1005-0957.2026.05.0516
针刺联合康复训练治疗儿童孤独症的疗效观察
Observation of the therapeutic efficacy of acupuncture plus rehabilitation training in treating childhood autism
摘要
Abstract
Objective To observe the clinical efficacy of acupuncture combined with rehabilitation training in treating childhood autism.Method Ninety-six patients with autism were randomized into an observation group or a control group,each consisting of 48 cases.The control group underwent behavioral analysis training;in addition,the observation group received brain-gut co-adjustment acupuncture treatment.Before and after treatment,the symptom score of traditional Chinese medicine(TCM),the autism behavior checklist(ABC)score,the childhood autism rating scale(CARS)score,the autism treatment evaluation checklist(ATEC)score,and the serum levels of brain-derived neurotrophic factor(BDNF)and γ-aminobutyric acid(GABA)were compared.The clinical efficacy was also compared between the two groups.Result After treatment,both groups demonstrated decreases in the TCM symptom,ABC,CARS,and ATEC scores(P＜0.05),and the scores in the observation group were lower than those in the control group(P＜0.05).After intervention,the serum BDNF level dropped in both groups(P＜0.05)and was lower in the observation group than in the control group(P＜0.05);the serum level of GABA increased in both groups(P＜0.05)and was higher in the observation group than in the control group(P＜0.05).The observation group achieved a total effective rate of 87.5%,higher than 64.6%in the control group(P＜0.05).Conclusion Brain-gut co-adjustment acupuncture plus rehabilitation training can reduce the TMC symptom score,alleviate clinical symptoms,and regulate serum GABA and BDNF levels in treating childhood autism.关键词
针刺疗法/孤独症/儿童/脑肠共调Key words
Acupuncture therapy/Autism/Child/Brain-gut co-adjustment分类
医药卫生引用本文复制引用
朱小健,黄群,张于凤,谢万忠..针刺联合康复训练治疗儿童孤独症的疗效观察[J].上海针灸杂志,2026,45(5):516-521,6.基金项目
荆州市科技技术发展项目(ZY2022312) （ZY2022312）
