世界睡眠医学杂志2026，Vol.13Issue(1)：5-7,3.DOI:10.3969/j.issn.2095-7130.2026.01.002
左乙拉西坦对癫痫患儿脑电图及睡眠质量的影响
Effect of Levetiracetam on Electroencephalogram and Sleep Quality in Children with Epilepsy
黄志珍 1戴梦园1
作者信息
- 1. 福建省龙岩市第二医院神经内科,龙岩,364000
- 折叠
摘要
Abstract
Objective:To observe the effect of levetiracetam on electroencephalogram(EEG)and sleep quality in children with epilepsy.Methods:A total of 30 children with epilepsy admitted to the Department of Neurology,The Second Hospital of Longyan from July 2023 to July 2025 were selected and randomly divided into a control group and an observation group using the coin-toss-ing method,with 15 cases in each group.The control group received sodium valproate,while the observation group received sodium valproate combined with levetiracetam.The adverse reactions,EEG parameters and sleep quality were compared between the two groups.Results:After treatment,α and β wave bands increased in both groups(P＜0.05),and were higher in the observation group than in the control group(P＜0.05).δ and θ wave bands decreased in both groups(P＜0.05),and were lower in the ob-servation group than in the control group(P＜0.05).The Pittsburgh Sleep Quality Index(PSQI)scores decreased in both groups after treatment(P＜0.05),and were lower in the observation group than in the control group(P＜0.05).There was no statistical-ly significant difference in the total incidence of adverse reactions between the two groups(P＞0.05).Conclusion:On the basis of sodium valproate treatment,the addition of levetiracetam can effectively improve EEG parameters and sleep quality in children with epilepsy without significantly increasing adverse reactions,demonstrating good safety.关键词
癫痫/儿童/脑电描记术/左乙拉西坦/睡眠质量Key words
Epilepsy/Children/Electroencephalography/Levetiracetam/Sleep quality分类
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黄志珍,戴梦园..左乙拉西坦对癫痫患儿脑电图及睡眠质量的影响[J].世界睡眠医学杂志,2026,13(1):5-7,3.
