世界针灸杂志（英文版）2026，Vol.36Issue(2)：118-123,6.DOI:10.1016/j.wjam.2026.03.002
穴位敏化理论在溃疡性结肠炎动态治疗中的体现
Acupoint sensitization theory in dynamic treatment for ulcerative colitis
摘要
Abstract
Ulcerative colitis(UC)is a recurrent chronic inflammatory bowel disease and its clinical assessment re-lies mainly on invasive examinations with a delayed response.The acupoint sensitization theory proposes that visceral pathological states can dynamically manifest at specific body surface sites through segmental neural connections,presenting as functional or morphological changes in acupoints.This article outlines the pathological progression of UC,and then systematically reviews the clinical manifestations and neuro-biological mechanisms of acupoint sensitization,covering multiple layers including viscero-somatic affer-ent convergence and spinal segmental sensitization,cutaneous neurogenic inflammation and peripheral sensitization amplification,sympathetic-sensory coupling and bidirectional somato-visceral modulation.On this basis,combined with limited existing clinical outcomes of acupoint sensitization in UC patients,the potential application value of this theory in UC disease assessment and acupuncture intervention is tentatively discussed.Finally,this paper points out the shortcomings of current research on acupoint sen-sitization in UC and proposes that future studies should focus on sensitization characterization of UC at different stages and lesion locations,as well as their correlations with disease activity.It also suggests that the development of multimodal and quantitative detection devices will advance the translational application of the acupoint sensitization theory in precise acupuncture treatment for UC.关键词
Acupoint sensitization/Ulcerative colitis/Dynamic treatment/Acupuncture and moxibustion/Mechanism researchKey words
Acupoint sensitization/Ulcerative colitis/Dynamic treatment/Acupuncture and moxibustion/Mechanism research引用本文复制引用
程泓怡,王智,张家绵,张恒,刘坤..穴位敏化理论在溃疡性结肠炎动态治疗中的体现[J].世界针灸杂志（英文版）,2026,36(2):118-123,6.基金项目
Supported by National Natural Science Foundation of China(General Program):82174513 （General Program）
Independent Topic Selection Project of Basic Research Operating Ex-penses,Institute of Acupuncture and Moxibustion,China Academy of Chinese Med-ical Sciences:ZZCZ2025-025 （）
Innovative Talent Special Project of Independent Topic Selection,Institute of Acupuncture and Moxibustion,China Academy of Chinese Medical Sciences:ZZ-JQ2023003. （）
