现代中医药2026，Vol.46Issue(3)：39-44,6.DOI:10.13424/j.cnki.mtcm.2026.03.006
当归治疗2型糖尿病心肌病的潜在作用机制及研究进展
The Potential Mechanism and Research Progress of the Treatment of Type 2 Diabetic Cardiomyopathy
摘要
Abstract
With the aging of society,the prevalence of diabetes-a common age-related metabolic disorder-has been steadily increasing.As a consequence,the incidence of diabetic cardiomyopathy(DCM),one of its major complications,has also risen significantly.DCM represents the most prevalent cardiovascular complication in patients with type 2 diabetes mel-litus(T2DM),characterized by structural and functional myocardial abnormalities independent of coronary artery disease or hypertension.This condition not only serves as a critical factor in cardiac impairment and heart failure among diabetic pa-tients but also constitutes a specific myocardial injury distinct from secondary damage caused by coronary artery disease.The pathogenesis of DCM typically involves inflammatory aging,oxidative stress,mitochondrial dysfunction,and metabolic dis-turbances.The traditional Chinese herb Angelica sinensis(Danggui)has demonstrated potential therapeutic value for DCM due to its diverse pharmacologically active components.This review elucidates the pathological mechanisms of DCM,the pri-mary active constituents of Angelica sinensis,and their mechanisms in ameliorating DCM,thereby providing novel insights into the relationship between diabetic cardiomyopathy and Angelica sinensis treatment.关键词
糖尿病心肌病/当归/作用机制/研究进展Key words
diabetic cardiomyopathy/angelica sinensis/mechanism of action/research progress分类
医药卫生引用本文复制引用
徐杰,牛屹泽,黄蕊,武春宇..当归治疗2型糖尿病心肌病的潜在作用机制及研究进展[J].现代中医药,2026,46(3):39-44,6.基金项目
甘肃省药品科研项目(2023QSMPA075) （2023QSMPA075）
