实用医学杂志2026，Vol.42Issue(10)：1681-1691,11.DOI:10.3969/j.issn.1006-5725.2026.10.001
成人隐匿性自身免疫性糖尿病微血管并发症研究进展
Recent advances in microvascular complications of latent autoimmune diabetes in adults
摘要
Abstract
Latent autoimmune diabetes in adults(LADA)is a distinct subtype of autoimmune diabetes.This condition is characterized by an autoimmune-mediated progressive decline in β-cell function,with microvascular pathology exhibiting unique pathological progression and clinical features.The development and progression of microvascular complications in LADA patients are associated with various factors,including genotyping,autoimmune mechanisms,and biomarkers.Investigating the underlying mechanisms and clinical characteristics of LADA is of significant clinical importance for early identification of high-risk populations,formulating individualized intervention strategies,and delaying the progression of complications.This review consolidates recent research advances in the field of LADA-related microvascular complications,aiming to systematically elucidate the patterns of their development and progression.It seeks to provide theoretical support and clinical guidance for early risk prediction,personalized treatment,and improved patient outcomes.关键词
成人隐匿性自身免疫性糖尿病/LADA/1型糖尿病/微血管并发症/糖尿病肾病/糖尿病视网膜病变/糖尿病神经病变Key words
latent autoimmune diabetes in adults/LADA/type 1 diabetes mellitus/microvascular complications/diabetic nephropathy/diabetic retinopathy/diabetic neuropathy分类
医药卫生引用本文复制引用
尚萌萌,邓婕,田利民..成人隐匿性自身免疫性糖尿病微血管并发症研究进展[J].实用医学杂志,2026,42(10):1681-1691,11.基金项目
甘肃省科技重大专项计划(编号:22ZD6FA033) （编号:22ZD6FA033）
