实用医学杂志2026，Vol.42Issue(10)：1729-1736,8.DOI:10.3969/j.issn.1006-5725.2026.10.006
广西地区成人超重肥胖与心血管代谢风险的关联及聚集特征分析:基于10万体检人群的横断面研究
Association and clustering of overweight/obesity with cardiometabolic risks in adults in Guangxi:A cross-sectional study of 100,000 health examination participants
摘要
Abstract
Objective To investigate the prevalence of overweight/obesity and its association with cardio-metabolic risk factors among adults in Guangxi and provide evidence for regional weight management and cardio-metabolic disease prevention.Methods A cross-sectional study recruited 108,804 adults who underwent health examinations at the People's Hospital of Guangxi Zhuang Autonomous Region from January to December 2024.The participants were classified according to BMI into underweight,normal weight,overweight,and obese groups.Mul-tivariate logistic regression,stratified and interaction analyses,risk factor clustering,and Cochran-Armitage trend tests were carried out.Results The prevalence rates of overweight,obesity,and central obesity were 35.95％,13.30％(combined 49.25％),and 26.6％,respectively.Overweight/obesity was independently associated with hypertension,hyperglycemia,dyslipidemia,and fatty liver,and the strongest association was observed for fatty liver(obese group:OR=25.03,95％CI:23.66-26.48,adjusted for age and sex).The combined analysis of BMI and central obesity indicated that individuals with both overweight/obesity and central obesity had the high-est metabolic risks,with odds ratios(ORs)(95％confidence intervals[CI])of 3.48(3.33-3.63)for hyperten-sion,3.35(3.17-3.55)for hyperglycemia,2.76(2.66-2.86)for dyslipidemia,and 14.18(13.64-14.74)for fatty liver.Sex-stratified analyses disclosed stronger associations of overweight/obesity with hyperglycemia and fatty liver in women,and with dyslipidemia and hypertension in men(all interaction P＜0.05).Age-stratified analyses demonstrated the strongest associations in the 18-29 age group,and these associations declined with age(interac-tion P＜0.001).From underweight to obesity,the mean number of risk factors increased from 0.32 to 2.22,and the proportion of individuals with ≥3 risk factors rose from 0.45％to 36.92％(trend x2=27753.48,P＜0.001).Conclusions The prevalence of overweight and obesity is notably high among adults in Guangxi.This high preva-lence acts as a crucial driver of cardiometabolic risk factor clustering,and there are significant sex-and age-related differences in these associations.Additionally,the co-occurrence of overweight/obesity and central obesity synergis-tically exacerbates metabolic risks.Therefore,targeted weight management and comprehensive prevention strate-gies customized to regional characteristics are necessary.关键词
广西地区/超重/肥胖/心血管代谢危险因素/横断面研究Key words
Guangxi/overweight/obesity/cardiometabolic risk factors/cross-sectional study分类
医药卫生引用本文复制引用
伍朝春,庞羽,李发添,包基荣..广西地区成人超重肥胖与心血管代谢风险的关联及聚集特征分析:基于10万体检人群的横断面研究[J].实用医学杂志,2026,42(10):1729-1736,8.基金项目
广西自然科学基金项目(编号:2023GXNSFAA026117) （编号:2023GXNSFAA026117）
广西壮族自治区中医药管理局科研课题(编号:Gzzc2019126) （编号:Gzzc2019126）
