中国防痨杂志2026，Vol.48Issue(6)：813-820,8.DOI:10.19982/j.issn.1000-6621.20250405
数字技术管理下老年结核病患者服药依从性现状及影响因素探讨
Status and influencing factors of medication adherence among elderly tuberculosis patients based on digital technologies
摘要
Abstract
Objective:To explore the status and influencing factors of medication adherence in elderly patients with tuberculosis based on digital technology management.Methods:With the convenience sampling method,220 elderly tuberculosis patients who were hospitalized at the Tuberculosis Diagnosis and Treatment Center of Hangzhou Red Cross Hospital from August 2024 to August 2025 and who received digital technology for medication adherence management after discharge were selected as the study participants.Data on demographic characteristics and disease-related variables were collected through medical record review.Medication adherence,activities of daily living,and family support were assessed via structured questionnaires.Univariate analysis and binary logistic regression were performed to explore the associations between these variables and medication adherence.Results:A total of 205 elderly tuberculosis patients were included,with 139(67.8％)in the medication compliance group and 66(32.2％)in the medication non-compliance group.Multivariate logistic analysis showed that skin allergic reactions caused by anti-tuberculosis drugs(OR=16.357,95％CI:1.683-158.968),gastrointestinal adverse reactions induced by anti-tuberculosis drugs(OR=3.804,95％CI:1.318-10.978),history of allergy to other medications(OR=10.782,95％CI:1.714-67.828),good follow-up response to digital technology(OR=0.317,95％CI:0.128-0.790),high family support(OR=0.085,95％CI:0.017-0.414),mild dependence on activities of daily living(OR=0.083,95％CI:0.008-0.901),and non-dependence on activities of daily living(OR=0.029,95％CI:0.001-0.675)were independent factors associated with medication adherence among elderly tuberculosis patients managed via digital technology(P＜0.05).Conclusion:The medication adherence of elderly patients with tuberculosis based on digital technology management is affected by the skin allergic reactions and gastrointestinal adverse reactions caused by anti-tuberculosis drugs,history of allergy to other medications,follow-up response to digital technology,daily living ability and family support level.The nursing staff should implement tailored interventions based on the influencing factors to improve the medication adherence under the digital health management model.关键词
数字依从性技术/结核/服药依从性/影响因素Key words
Digital adherence technology/Tuberculosis/Medication compliance/Influencing factors分类
医药卫生引用本文复制引用
张玥,黄金鹏,高丹,凌琳..数字技术管理下老年结核病患者服药依从性现状及影响因素探讨[J].中国防痨杂志,2026,48(6):813-820,8.基金项目
浙江省医药卫生科技计划项目(2025KY1123) （2025KY1123）
浙江省中医药科技计划项目(2025ZL443) Zhejiang Provincial Medical and Health Science and Technology Project(2025KY1123) （2025ZL443）
Zhejiang Provincial Traditional Chinese Medicine Science and Technology Planning Project(2025ZL443) （2025ZL443）
