中国普通外科杂志2026，Vol.35Issue(3)：429-435,7.DOI:10.7659/j.issn.1005-6947.250567
"黏膜优先愈合"理论指导下的胰管空肠吻合术
Pancreaticojejunostomy guided by the theory of mucosal priority healing
摘要
Abstract
Pancreaticojejunostomy is a critical step in pancreatoduodenectomy,and its quality directly affects the incidence of postoperative complications,including pancreatic fistula and hemorrhage.Despite continuous technical improvements,the risk of severe complications remains substantial.Based on pathological observations and histological analyses,and considering the migration characteristics of intestinal mucosa,we propose the concept of"mucosal priority healing".This concept emphasizes shortening the migration distance of intestinal mucosa and reducing the number of anastomotic sutures to facilitate rapid apposition and healing between the jejunal mucosa and the pancreatic duct epithelium.Pancreaticojejunostomy guided by this concept optimizes the healing mechanism of the anastomosis,ensures adequate pancreatic drainage,and may reduce the risk of severe complications such as postoperative hemorrhage,reoperation,and mortality.This article systematically reviews the theoretical basis,technical features,and clinical outcomes of this approach,and discusses future research directions in the context of current evidence,aiming to provide insights into the standardization and precision of pancreaticojejunostomy.关键词
胰管空肠吻合术/黏膜优先愈合/胰腺瘘/手术后出血Key words
Pancreaticojejunostomy/Mucosal Priority Healing/Pancreatic Fistula/Postoperative Hemorrhage分类
医药卫生引用本文复制引用
吴士兴,李建刚,耿诚,王诚,张博林,阿提古·阿布都外力,徐新建,汤朝晖.."黏膜优先愈合"理论指导下的胰管空肠吻合术[J].中国普通外科杂志,2026,35(3):429-435,7.基金项目
新疆维吾尔自治区"天山英才"医药卫生高层次人才—领军人才基金资助项目(TSYC202301A036) （TSYC202301A036）
国家自然科学基金资助项目(82160491) （82160491）
新疆维吾尔自治区科学技术厅自然科学基金资助项目(2021D01C424). （2021D01C424）
