刘振越 1刘心娟 1于剑锋 1郭怀珠 1高颖新 1李超 1卢迪 1刘晓1
作者信息
- 1. 首都医科大学附属北京朝阳医院消化内科,北京 100020
- 折叠
摘要
Abstract
Objective To investigate the influencing factors of respiratory-related adverse events(such as cough and hypoxemia)in patients with reflux esophagitis(RE)undergoing painless gastroscopy,and to construct a nomogram model for this population.Methods A total of 268 patients diagnosed with RE by painless gastroscopy were enrolled from three campuses of Beijing Chaoyang Hospital Affiliated to Capital Medical University between January 25,2025 and January 15,2026.Clinical data were collected via a questionnaire survey after the patients regained consciousness from anesthesia.According to the occurrence of respiratory-related adverse events during gastroscopy,the patients were divided into the adverse event group(n=80)and the non-adverse event group(n=188).Baseline characteristics,RE grading,Helicobacter pylori(Hp)infection,hiatal hernia/cardiac relaxation and other relevant factors were compared between the two groups.Univariate and multivariate logistic regression analyses were performed to identify the independent risk factors,and a dynamic nomogram model was further constructed based on the identified factors.Results The overall incidence of respiratory-related adverse events was 29.9％(80/268),including 23 cases of hypoxemia(8.5％),56 cases of cough(≥5 times,20.8％),and 1 case of aspiration(0.3％).Multivariate logistic regression analysis revealed that habitual snoring(OR=2.048,95％CI 1.039-4.039),smoking history(OR=3.144,95％CI 1.449-6.822),hiatal hernia/cardiac relaxation(OR=10.290,95％CI 5.045-20.97),elevated Los Angeles classification(OR=2.172,95％CI 1.224-3.857)and gastric content volume(per 10 mL,OR=1.100,95％CI 1.001-1.209)were independent risk factors for respiratory-related adverse events(P＜0.05).Conclusion For RE patients undergoing painless gastroscopy,habitual snoring,smoking history,hiatal hernia/cardiac relaxation,elevated Los Angeles classification and increased gastric content volume are independent risk factors for respiratory-related adverse events during the examination.Based on these factors,medical staff can conduct risk stratification for RE patients before painless gastroscopy,and thus implement appropriate preventive and protective measures.关键词
反流性食管炎/无痛胃镜/呼吸相关不良事件/列线图模型Key words
reflux esophagitis/painless gastroscope/respiratory related adverse events/linechart model分类
医药卫生
