中国兽医杂志2026，Vol.62Issue(5)：29-35,7.DOI:10.20157/j.cnki.zgsyzz.2026.05.004
鸽源沙门菌的分离鉴定及其耐药性和毒力基因分析
Isolation,Identification and Analysis of Drug Resistance and Virulence Genes of Pigeon-Derived Salmonella spp.
摘要
Abstract
A suspected Salmonella infection occurred in a large-scale pigeon farm in Hebei Province.To identify the pathogen and characterize its drug resistance and virulence profiles,liver tissues from dead pigeons were subjected to bacterial isolation and culture.The isolates were identified through morphological identification,biochemical tests,serotyping,and 16S rRNA gene sequencing.Drug susceptibility testing and whole-genome sequencing were further performed to analyze the resistance phenotype,drug resistance genes,and virulence genes of the isolate.The results showed that one strain of Salmonella typhimurium was isolated.Drug susceptibility testing indicated that the isolate was resistant to neomycin and streptomycin.Whole-genome sequencing analysis revealed that the isolate carried 22 drug resistance genes and 137 virulence genes.These results indicate that a pigeon-derived Salmonella typhimurium strain carrying multiple drug resistance and virulence genes was successfully isolated in this study,providing a reference for the prevention,control,medication,and further research on pigeon-derived Salmonella typhimurium.关键词
鸽/鼠伤寒沙门菌/分离鉴定/耐药性/毒力基因Key words
pigeon/Salmonella typhimurium/isolation and identification/drug resistance/virulence gene分类
农业科技引用本文复制引用
习硕,沈佳,靳换,赵蕾,史爱华,崔丽娜,章振华..鸽源沙门菌的分离鉴定及其耐药性和毒力基因分析[J].中国兽医杂志,2026,62(5):29-35,7.基金项目
北京市农林科学院创新能力建设(KJCX20240338,KJCX20230424) （KJCX20240338,KJCX20230424）
