中国中西医结合影像学杂志2026，Vol.24Issue(3)：296-300,5.DOI:10.3969/j.issn.1672-0512.2026.03.008
静息态fMRI对脊髓损伤患者自发性脑活动改变的分析
Analysis of spontaneous brain activity changes in patients with spinal cord injury using resting-state fMRI
摘要
Abstract
Objective:To investigate the spontaneous brain activity changes in patients with spinal cord injury by resting-state fMRI.Methods:43 patients with spinal cord injury were prospectively enrolled as the injury group,and 43 healthy volunteers matched in age,sex and education level were recruited as the control group.All subjects underwent resting-state fMRI,and regional homogeneity(ReHo)and fractional amplitude of low-frequency fluctuation(fALFF)analyses were performed,respectively.Two-sample t-test was used to compare the differences between groups.Results:Compared with the control group,the injury group showed brain functional reorganization.The ReHo values in the right middle frontal gyrus and Brodmann 9 area increased significantly,while the ReHo values in the bilateral orbital medial frontal gyri,Brodmann area 10,the left orbital inferior frontal gyrus and left insula decreased significantly.The fALFF values of the right superior parietal gyrus and the right postcentral gyrus increased significantly,while the fALFF values of the right precuneus and left posterior cingulate gyrus significantly decreased.Conclusion:The changes in spontaneous neuronal activity in the brain regions related to sensory-motor networks and cognitive control in patients with spinal cord injury provide important imaging evidence for understanding the neural plasticity after spinal cord injury.关键词
脊髓损伤/静息态功能性磁共振/局部一致性/分数低频振幅/自发性脑活动Key words
Spinal cord injuries/Resting-state functional magnetic resonance imaging/Regional homogeneity/Fractional low frequency amplitude/Spontaneous brain activity分类
医药卫生引用本文复制引用
丛欣莹,张红霞,袁媛,于卫永,陈振波..静息态fMRI对脊髓损伤患者自发性脑活动改变的分析[J].中国中西医结合影像学杂志,2026,24(3):296-300,5.基金项目
中国康复研究中心科研基金项目(2021zx-Q14). （2021zx-Q14）
