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转录组测序分析在动物子宫内膜炎上的应用

李张 蓝群 李铭 练胜举 贺申海 李国强 刘梅

中国猪业2026,Vol.21Issue(2):85-94,10.
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中国猪业2026,Vol.21Issue(2):85-94,10.DOI:10.16174/j.issn.1673-4645.2026.02.009

转录组测序分析在动物子宫内膜炎上的应用

Application of transcriptome sequencing analysis in animal endometritis

李张 1蓝群 1李铭 1练胜举 1贺申海 1李国强 1刘梅1

作者信息

  • 1. 湖南农业大学动物科学技术学院,湖南长沙 410128||岳麓山实验室畜禽品种创制中心,湖南长沙 410128
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摘要

Abstract

Endometritis is a common reproductive disease in animal husbandry,frequently occurring in dairy cows,sows,and sheep.It can lead to reduce milk production,decrease reproductive efficiency,and increase culling rates,not only affecting animal productivity but also significantly diminishing economic returns.Due to its diverse clinical manifestations,complex etiology,and high incidence,it has long been a subject of significant concern.In recent years,advancements in high-throughput sequencing technologies have enabled transcriptomics-based bioinformatics analyses to deeply explore gene expression patterns associated with endometritis,providing technical support for elucidating its regulatory mechanisms.This review summarized the primary applications and advancements of transcriptome sequencing in research related to uterine endometritis in female livestock.It systematically identified key differentially expressed genes and signaling pathways associated with the disease,offering new insights into strategies for improving uterine endometritis management in female livestock.This work aimed to provide a theoretical foundation for enhancing reproductive health and ultimately improving reproductive performance in female livestock.

关键词

母畜/子宫内膜炎/转录组学/关键基因/分子机制

Key words

female animals/endometritis/transcriptomics/key genes/molecular mechanisms

分类

农业科技

引用本文复制引用

李张,蓝群,李铭,练胜举,贺申海,李国强,刘梅..转录组测序分析在动物子宫内膜炎上的应用[J].中国猪业,2026,21(2):85-94,10.

基金项目

国家重点研发计划项目(2023YFD1300503) (2023YFD1300503)

生物育种-国家科技重大专项项目(2023ZD04046) (2023ZD04046)

中国猪业

1673-4645

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