中医药信息2026，Vol.43Issue(5)：60-66,7.DOI:10.19656/j.cnki.1002-2406.20260509
基于真实世界的电针治疗慢性萎缩性胃炎临床疗效分析
Analysis of Clinical Efficacy of Electroacupuncture in the Treatment of Chronic Atrophic Gastritis Based on Real World
摘要
Abstract
Objective To evaluate the clinical efficacy of electroacupuncture in the treatment of chronic atrophic gastritis(CAG).Methods A prospective,self-controlled study was conducted.A total of 30 CAG patients in the Outpatient Department of Acupuncture and Rehabilitation in The First Affiliated Hospital of Anhui University of Chinese Medicine from September 2023 to May 2024 were enrolled.All patients received electroacupuncture treatment.The treatment schedule was set at two sessions per week.Ten sessions constituted one treatment course,followed by a one-week interval.The entire intervention comprised two courses,for a total treatment duration of 20 weeks.Changes in traditional Chinese medicine(TCM)symptom individual score and total scores,gastroscopic histopathology(atrophy,intestinal metaplasia,dysplasia,and inflammatory activity)individual score and total scores,HAMA(Hamilton Anxiety Rating Scale)scores,HAMD(Hamilton Depression Rating Scale)scores,serum gastric function indicators(PGⅠ,PGR,G-17,and PGⅡ)were observed before and after treatment.The efficacy of TCM syndromes and gastroscopic efficacy were assessed.Results The total effective rate of TCM syndromes was 93.33%(28/30),while the total effective rate of gastroscopy was 83.33%(25/30).Compared with treatment before,All TCM symptom individual and total scores decreased significantly(P<0.05);Histological individual and total scores of atrophy,intestinal metaplasia,and inflammatory activity,as well as HAMA and HAMD scores,decreased significantly(P<0.01).While the histopathological score for dysplasia showed no significant change,and the difference was not statistically significant.(P>0.05);Serum indicators including PGⅠ,PGR,and G-17 increased(P<0.05),while PGⅡ decreased(P<0.05).Conclusion Electroacupuncture can effectively relieve clinical symptoms of CAG patients,significantly improve gastroscopic and histopathology findings,alleviate anxiety and depression,and regulate serum gastric function indicators.It exhibits favorable clinical efficacy and a good safety profile.关键词
电针/慢性萎缩性胃炎/胃镜/病理/胃功能Key words
Electroacupuncture/Chronic atrophic gastritis(CAG)/Gastroscopy/Pathology/Gastric function引用本文复制引用
杨晓璇,樊吟秋,白甫江,朱大为,唐友斌..基于真实世界的电针治疗慢性萎缩性胃炎临床疗效分析[J].中医药信息,2026,43(5):60-66,7.基金项目
安徽省科学技术厅临床医学研究转化专项项目(202304295107020121) （202304295107020121）
