首页|期刊导航|Green Synthesis and Catalysis|Modulating regioselectivity of CYP107J3-catalyzed isophorone hydroxylation by disrupting the hydrophobic balance of the substrate binding pocket
Green Synthesis and Catalysis2026,Vol.7Issue(2):P.198-204,7.DOI:10.1016/j.gresc.2024.05.007
Modulating regioselectivity of CYP107J3-catalyzed isophorone hydroxylation by disrupting the hydrophobic balance of the substrate binding pocket
摘要
关键词
Isophorone hydroxylation/P450CYP107J3/Mechanism of regioselectivity/Multiscale simulation/Enzyme engineering分类
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Meng Dai,Xiaojuan Yu,Xiaogang Peng,Zhiyong Guo,Huili Yu,Aitao Li..Modulating regioselectivity of CYP107J3-catalyzed isophorone hydroxylation by disrupting the hydrophobic balance of the substrate binding pocket[J].Green Synthesis and Catalysis,2026,7(2):P.198-204,7.基金项目
supported by the National Key Research and Development Program of China(No.2021YFC2102400) (No.2021YFC2102400)
the Key Science and Technology Innovation Project of Hubei Province(No.2021BAD001) (No.2021BAD001)
the Innovation Base for Introducing Talents of Discipline of Hubei Province(No.2019BJH021) (No.2019BJH021)
the Research Program of State Key Laboratory of Biocatalysis and Enzyme Engineering. ()