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Atomic iron-engineered dual-modal nanozyme enhances tumortargeted chemodynamic/photothermal synergistic therapy

Cai-Shi Lin Wenhao Shi Yanfei Zhu Weiheng Ma Yongjian Ai Jing Wang Qionglin Liang Meng-Qi He

Nano Research2026，Vol.19Issue(5)：P.809-825,17.

Nano Research2026，Vol.19Issue(5)：P.809-825,17.DOI:10.26599/NR.2025.94908256

Atomic iron-engineered dual-modal nanozyme enhances tumortargeted chemodynamic/photothermal synergistic therapy

Cai-Shi Lin ¹Wenhao Shi ²Yanfei Zhu ¹Weiheng Ma ¹Yongjian Ai ³Jing Wang ¹Qionglin Liang ²Meng-Qi He¹

作者信息

1. State Key Laboratory of Respiratory Health and Multimorbidity,Institute of Basic Medical Sciences Chinese Academy of Medical Sciences,School of Basic Medicine Peking Union Medical College,Beijing 100005,China
2. MOE Key Laboratory of Bioorganic Phosphorus Chemistry&Chemical Biology,Department of Chemistry,Laboratory of Flexible Electronics Technology,Center for Synthetic and Systems Biology,Tsinghua University-Peking University Joint Centre for Life Sciences,Tsinghua University,Beijing 100084,China
3. MOE Key Laboratory of Bioorganic Phosphorus Chemistry&Chemical Biology,Department of Chemistry,Laboratory of Flexible Electronics Technology,Center for Synthetic and Systems Biology,Tsinghua University-Peking University Joint Centre for Life Sciences,Tsinghua University,Beijing 100084,China MOE Key Laboratory of Precision Nutrition and Food Quality,Department of Nutrition and Health,China Agricultural University,Beijing 100193,China
折叠

摘要

关键词

single-Fe-atom nanozyme/combinatorial cancer therapy/photothermal activity/peroxidase-like activity/synergistic therapy

分类

医药卫生

引用本文复制引用

Cai-Shi Lin,Wenhao Shi,Yanfei Zhu,Weiheng Ma,Yongjian Ai,Jing Wang,Qionglin Liang,Meng-Qi He..Atomic iron-engineered dual-modal nanozyme enhances tumortargeted chemodynamic/photothermal synergistic therapy[J].Nano Research,2026,19(5):P.809-825,17.

基金项目

supported by the National Natural Science Foundation of China(Nos.22304099,82304442,and 82574366) （Nos.22304099,82304442,and 82574366）

Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(Nos.2024-I2M-3-013 and 2023-I2M-2-001) （Nos.2024-I2M-3-013 and 2023-I2M-2-001）

the National Key R&D Program of China(Nos.2023YFC3504401 and 2022YFA1103403) （Nos.2023YFC3504401 and 2022YFA1103403）

Beijing Natural Science Foundation(No.L256002) （No.L256002）

Beijing Outstanding Young Scientist Program(No.JWZQ20240101019) （No.JWZQ20240101019）

Young Elite Scientist Sponsorship Program of the Beijing Association for Science and Technology(Nos.BYESS2023166 and BYESS2024140) （Nos.BYESS2023166 and BYESS2024140）

State Key Laboratory Special Fund(No.2060204) （No.2060204）

China Postdoctoral Science Foundation Funded Project(Nos.2023T160372,2022M711779,and BX20220160)。（Nos.2023T160372,2022M711779,and BX20220160）

Nano Research

ISSN：1998-0124

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