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MFAP2 promotes metastasis and drug resistance by regulating epithelial-to-mesenchymal transition through EGFR signaling pathway in colorectal cancer cells

Zhicheng He Yuanzhi Chen Shuting Yang Cheng Chen Yingying He Shubai Liu

Genes & Diseases2026，Vol.13Issue(3)：P.573-590,18.

Genes & Diseases2026，Vol.13Issue(3)：P.573-590,18.DOI:10.1016/j.gendis.2025.101800

MFAP2 promotes metastasis and drug resistance by regulating epithelial-to-mesenchymal transition through EGFR signaling pathway in colorectal cancer cells

Zhicheng He ¹Yuanzhi Chen ²Shuting Yang ²Cheng Chen ²Yingying He ³Shubai Liu¹

作者信息

1. State Key Laboratory of Phytochemistry and Natural Medicines,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming,Yunnan 650201,China University of Chinese Academy of Sciences,Beijing 100049,China
2. State Key Laboratory of Phytochemistry and Natural Medicines,Kunming Institute of Botany,Chinese Academy of Sciences,Kunming,Yunnan 650201,China
3. School of Chemical Science & Technology,Yunnan University,Kunming,Yunnan 650091,China
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摘要

关键词

Colorectal cancer/Epithelial-to-mesenchymal transition/Metastasis/MFAP2/Therapeutic target/Virtual screening

分类

医药卫生

引用本文复制引用

Zhicheng He,Yuanzhi Chen,Shuting Yang,Cheng Chen,Yingying He,Shubai Liu..MFAP2 promotes metastasis and drug resistance by regulating epithelial-to-mesenchymal transition through EGFR signaling pathway in colorectal cancer cells[J].Genes & Diseases,2026,13(3):P.573-590,18.

基金项目

supported by the grant for outstanding talent from abroad by Chinese Academic of Science and Startup Support Funding(No.E0241211H1 to Shubai Liu) （No.E0241211H1 to Shubai Liu）

State Key Laboratory of Phytochemistry and Natural Medicines,Kunming Institute of Botany,the Chinese Academy of Sciences,China(No.Y8677211K1,Y8690211Z1 to Shubai Liu). （No.Y8677211K1,Y8690211Z1 to Shubai Liu）

Genes & Diseases

ISSN：2352-4820

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