首页|期刊导航|Genes & Diseases|Targeting MDK alleviates bone loss via dual regulation of osteogenic differentiation and inflammatory cytokine expression

Targeting MDK alleviates bone loss via dual regulation of osteogenic differentiation and inflammatory cytokine expression

Xieyidai Ruze Yutong Hu Xiongyi Wang Houfu Lai Ruizhi Zhang Sheng Pan Jiajun Zhang Yike Wang Simin Yun Ying Xu Junjie Li Youjia Xu

Genes & Diseases2026，Vol.13Issue(3)：P.393-408,16.

Genes & Diseases2026，Vol.13Issue(3)：P.393-408,16.DOI:10.1016/j.gendis.2025.101931

Targeting MDK alleviates bone loss via dual regulation of osteogenic differentiation and inflammatory cytokine expression

Xieyidai Ruze ¹Yutong Hu ¹Xiongyi Wang ¹Houfu Lai ¹Ruizhi Zhang ¹Sheng Pan ¹Jiajun Zhang ¹Yike Wang ¹Simin Yun ¹Ying Xu ²Junjie Li ³Youjia Xu¹

作者信息

1. Department of Orthopedics,Department of Osteoporosis,The Second Affiliated Hospital of Soochow University,Suzhou,Jiangsu 215004,China
2. Jiangsu Key Laboratory of Neuropsychiatric Diseases and Cambridge-Su Genomic Resource Center,Medical College of Soochow University,Suzhou,Jiangsu 215000,China
3. Department of Orthopedics,Department of Osteoporosis,The Second Affiliated Hospital of Soochow University,Suzhou,Jiangsu 215004,China The First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine),Hangzhou,Zhejiang 310006,China
折叠

摘要

关键词

Growth factors/Inflammatorycytokines/MDK/Osteoblast/Targeted therapy

分类

医药卫生

引用本文复制引用

Xieyidai Ruze,Yutong Hu,Xiongyi Wang,Houfu Lai,Ruizhi Zhang,Sheng Pan,Jiajun Zhang,Yike Wang,Simin Yun,Ying Xu,Junjie Li,Youjia Xu..Targeting MDK alleviates bone loss via dual regulation of osteogenic differentiation and inflammatory cytokine expression[J].Genes & Diseases,2026,13(3):P.393-408,16.

基金项目

supported by the Natural Science Foundation of China(No.82372455) （No.82372455）

Jiangsu Provincial Medical Key Laboratory Cultivation Unit(China)(No.JSDW202254) （China）

Special Project of"Technological Innovation"Project of CNNC Medical Industry Co.,Ltd.,China(No.ZHYLZD2023001) （No.ZHYLZD2023001）

Zhejiang Provincial Natural Science Foundation of China(No.LBZ24H060001). （No.LBZ24H060001）

Genes & Diseases

ISSN：2352-4820

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