川北医学院学报2026，Vol.41Issue(5)：552-556,5.DOI:10.3969/j.issn.1005-3697.2026.05.007
多模态超声评估颈动脉易损斑块与脑卒中发病的相关性
Correlation between multimodal ultrasound assessment of carotid vulnerable plaque and the onset of stroke
摘要
Abstract
Objective:To investigate the value of multimodal ultrasound technology in assessing the characteristics of carotid vulnerable plaques and analyze its correlation with the onset of ischemic stroke.Methods:A total of 93 patients were selected as study subjects,including 70 in the stroke group and 23 in the control group(without a history of stroke).All participants underwent conventional ultrasound,contrast-enhanced ultrasound(CEUS),and shear wave elastography(SWE)examinations.The differences in morphological features,enhanced intensity(EI),area under the curve(AUC),and Young's modulus values of plaques between the two groups were compared.Logistic regression analysis was used to identify independent risk factors for stroke onset.Results:The maximum plaque thickness was greater in the stroke group,with a higher proportion of hypoechoic,irregularly shaped,and fibrous cap defects(P<0.05).CEUS showed that the EI and AUC of plaques in the stroke group were higher than those in the control group(P<0.05).SWE measurements revealed that the Young's modulus values of plaques in the stroke group were lower than those in the control group(P<0.05).Multivariate Logistic regression analysis indicated that EI(OR=1.432,95%CI:1.152～1.781)and SWE Young's modulus value(OR=0.921,95%CI:0.883～0.961)were independent influencing factors for stroke onset.Conclusion:The combined application of multimodal ultrasound provides a comprehensive assessment of carotid plaque vulnerability.Rich intraplaque neovascularization(increased EI)and soft plaque texture(decreased SWE Young's modulus value)are independent influencing factors of stroke onset.Prospective studies should be conducted in the future to further explore the causal relationship.关键词
多模态超声/颈动脉易损斑块/脑卒中/超声造影/剪切波弹性成像/危险因素Key words
Multimodal ultrasound/Carotid vulnerable plaque/Ischemic stroke/Contrast-enhanced ultrasound(CEUS)/Shear wave elastography(SWE)/Risk factors分类
医药卫生引用本文复制引用
张青,马宁帅,吴静,于粒粒..多模态超声评估颈动脉易损斑块与脑卒中发病的相关性[J].川北医学院学报,2026,41(5):552-556,5.基金项目
四川省医学会科研项目(2024HR122) （2024HR122）
