成都中医药大学学报2026，Vol.49Issue(3)：95-100,6.DOI:10.13593/j.cnki.51-1501/r.2026.03.015
基于郭子光"人-症-病-证"体系探析神经性皮炎中医辨治方案
TCM Diagnostic and Therapeutic Plan for Neurodermatitis Based on Guo Ziguang's"Human-Symptom-Disease-Syndrome"System
摘要
Abstract
Neurodermatitis is characterized by lichenoid skin lesions and paroxysmal intense itching,with a prolonged course and high recurrence rate.Western medical treatments,particularly corticosteroids,face challenges such as unstable efficacy,high relapse rates,and significant side effects.Based on Guo Ziguang's"Human-Symptom-Disease-Syndrome"system,this study constructs a novel TCM diagnostic and therapeutic approach.Breaking through the limitations of traditional syndrome differentiation,it proposes for the first time that"Wind-Damp-Heat-Toxin stasis obstructing the skin,with Lung-Spleen deficiency"serves as the common core pathogenesis.A hierarchical framework of"human(holistic)-symptom(main manifestations)-disease(shared pathogenesis)-syndrome(individual variations)"is established to clarify recurrence mechanisms.Dynamic stage-specific treatment is implemented:in the acute phase,in-sect-based medications combined with Heat-clearing and Blood-cooling herbs are emphasized to rapidly interrupt the itch-scratch cycle,while the remission phase shifts to Lung-Spleen tonification,Blood activation,and collateral dredging to consolidate therapeutic effects and prevent relapse.A foundational formula,"Zhiyang Yufu Decoction",was developed,with modular modifications based on syn-drome types,forming a"one-core-formula,multi-syndrome adaptation"model.This protocol integrates hierarchical differentiation with dynamic stage adjustment,balancing rapid itch relief,standardized operation,and long-term recurrence prevention.It offers a new paradigm for neurodermatitis treatment that harmonizes TCM holistic principles with modern diagnostic logic.关键词
神经性皮炎/人-症-病-证/共性核心病机/止痒愈肤汤/病证结合Key words
Neurodermatitis/Human-Symptom-Disease-Syndrome/Common core pathogenesis/Zhiyang Yufu Decoction/Integration of disease and syndrome分类
医药卫生引用本文复制引用
蒋萃,何欣怡,袁世清,田茸,叶莹,江泳..基于郭子光"人-症-病-证"体系探析神经性皮炎中医辨治方案[J].成都中医药大学学报,2026,49(3):95-100,6.基金项目
四川省中管局中医药科研专项(2024MS569) （2024MS569）
成都中医药大学教改项目(JGYB202324) （JGYB202324）
成都中医药大学杏林人才项目(CCCX2023002) （CCCX2023002）
