佛山科学技术学院学报（自然科学版）2026，Vol.44Issue(3)：65-70,6.
基于拉曼光谱鉴别三种冰片的特征图谱
Characteristic spectra for the identification of three types of Borneol based on Raman spectroscopy
摘要
Abstract
Objective Due to the extremely high similarity among the three types of borneol(Borneolum,Borneolum syntheticum,and l-Borneolum),Raman spectroscopy is used to establish the characteristic spectra for the rapid analysis of these three types of borneol,enriching the research data on the chemical components of borneol and providing a basis for the quality control of borneol.Methods Macroscopic identification,thin-layer chromatography(TLC)identification,specific rotation measurement,gas chromatography(GC),and Raman spectroscopy were used to identify the three types of borneol.Results The macroscopic characteristics of Borneolum,Borneolum syntheticum,and l-Borneolum are similar,with slight differences in shape,size,and color;their thin-layer chromatography shows high similarity,while significant differences were observed in in optical rotation;gas chromatography can identify the three based on the calculation of component contents from the chromatograms,and each has a unique Raman spectral"fingerprint"pattern.Conclusion Raman spectroscopy can quickly and non-destructively identify Borneolum,Borneolum syntheticum,and l-Borneolum,which is consistent with the test results of other methods.This method can provide a reference basis for their quality control and rational application.关键词
天然冰片/合成冰片/艾片/拉曼光谱/性状鉴别Key words
Borneolum/Borneolum syntheticum/l-Borneolum/Raman spectroscopy/morphological identification分类
医药卫生引用本文复制引用
谢倩,练卓,朱成义,刘明香,桂怡玲,马荣..基于拉曼光谱鉴别三种冰片的特征图谱[J].佛山科学技术学院学报（自然科学版）,2026,44(3):65-70,6.基金项目
广东省基础与应用基础研究基金项目-粤佛联合基金(2023A1515110768) （2023A1515110768）
广东省高校科研项目(2024KQNCX147) （2024KQNCX147）
佛山市科学技术局项目(2320001007331) （2320001007331）
