分子影像学杂志2026，Vol.49Issue(5)：611-616,6.DOI:10.12122/j.issn.1674-4500.2026.05.07
常规磁共振T2WI影像可诊断≥5mm颅内动脉瘤
Conventional magnetic resonance T2-weighted imaging can diagnose intracranial aneurysms≥5 mm
摘要
Abstract
Objective To evaluate the diagnostic value of conventional magnetic resonance T2WI for intracranial aneurysms(IAs)≥5 mm,aiming to reduce the rates of missed and uncertain diagnosis.Methods We retrospectively collected magnetic resonance T2WI data of 151 patients with IAs≥5 mm,confirmed by computed tomography angiography(CTA),magnetic resonance angiography(MRA),or digital subtraction angiography(DSA),at Sir Run Run Shaw Hospital,Zhejiang University School of Medicine,from January 2019 to December 2024.A total of 162 IAs from the 151 patients were identified and categorized into a missed-diagnosis group,an uncertain-diagnosis group,and a confirmed-diagnosis group based on diagnostic difficulty.The impacts of aneurysm size,location,and T2-vascular flow void sign on the diagnosis of IAs were analyzed among the three groups.Additionally,the inter-observer agreement between two radiologists was evaluated.Results Among the 162 IAs,the proportions of the missed-diagnosis,uncertain-diagnosis,and confirmed-diagnosis groups were 13.6%(22/162),34.0%(55/162),and 52.4%(85/162),respectively.The aneurysm size in the confirmed-diagnosis group[10.90(8.20,13.15)mm]was significantly larger than that in the uncertain-diagnosis group[6.20(5.60,7.90)mm,P_corr<0.05]and the missed-diagnosis group[5.55(5.18,6.55)mm,P_corr<0.05],while no significant difference was observed between the uncertain and missed diagnosis groups(P_corr=0.397).IAs were predominantly located in the middle cerebral artery,ophthalmic segment of the internal carotid artery,communicating segment of the internal carotid artery,and vertebral artery,with no significant difference in location distribution among the three groups(P=0.825).The proportions of complete versus incomplete T2-vascular flow void sign in the missed-diagnosis,uncertain-diagnosis,and confirmed-diagnosis groups were 72.7%(16/22)vs 27.3%(6/22),67.3%(37/55)vs 32.7%(18/55),and 57.5%(49/85)vs 42.4%(36/85),respectively(P=0.306).Among the 151 patients,subarachnoid hemorrhage occurred in 3 cases.The inter-observer agreement between the two radiologists was excellent(Kappa=0.890,95%CI:0.839～0.941,P<0.05).Conclusion Conventional magnetic resonance T2WI demonstrates potential clinical value in the diagnosis of IAs≥5 mm.Accurate identification of T2WI features of IAs is expected to improve diagnostic accuracy and reduce complications such as subarachnoid hemorrhage.关键词
磁共振成像/颅内动脉瘤/计算机断层扫描血管造影/磁共振血管成像/数字减影血管造影Key words
magnetic resonance imaging/intracranial aneurysm/computed tomography angiography/magnetic resonance angiography/digital subtraction angiography引用本文复制引用
姚发明,邵丽敏,朱姬莹,朱庆庆,俞飞丹,吕骏晖,韩志江..常规磁共振T2WI影像可诊断≥5mm颅内动脉瘤[J].分子影像学杂志,2026,49(5):611-616,6.基金项目
浙江省自然科学基金(ZCLQN26H0901) （ZCLQN26H0901）
浙江省卫生健康行业科技计划(委省共建项目)(WKJ-ZJ-26047) （委省共建项目）
