西部中医药2026，Vol.39Issue(6)：49-54,6.DOI:10.12174/j.issn.2096-9600.2026.06.11
黄芪桂枝五物汤治疗神经根型颈椎病的贝叶斯Meta分析
Bayesian Meta-Analysis of Huangqi Guizhi Wuwu Decoction in the Treatment of Cervical Radiculopathy
摘要
Abstract
Objective:To assess the efficacy and safety of Huangqi Guizhi Wuwu decoction in the treatment of cervical radiculopathy(CR)using Bayesian meta-analysis.Methods:Randomized controlled trials(RCTs)on Huangqi Guizhi Wuwu Decoction for the treatment of CR were retrieved from PubMed,Embase,Cochrane Library,and China National Knowledge Infrastructure(CNKI)databases from their inception to March 2023.Two independent researchers performed literature screening and data extraction.Bias risk assessment was conducted using RevMan 5.3 software,and Bayesian meta-analysis was performed using Stata 14.0 software.Results:A total of 15 randomized controlled trials were included.Bayesian random-effects meta-analysis showed that,compared with other therapies,Huangqi Guizhi Wuwu Decoction significantly improved the total effective rate(SMD=3.58,95%CI:3.18-7.02,P＜0.000 01),VAS scores(SMD=-1.03,95%CI:-1.96--0.10,P=0.03),the scores of symptoms and body signs(SMD=-2.13,95%CI:-3.18--1.08,P＜0.001),and cervical function score(SMD=4.92,95%CI:4.15-5.69,P＜0.001),with low incidence of adverse reactions(SMD=-0.01,95%CI:-0.03--0.01,P=0.47).Conclusion:Huangqi Guizhi Wuwu decoction could improve the clinical efficacy for CR patients,effectively alleviate symptoms,enhance quality of life,and has a favorable safety profile.关键词
颈椎病,神经根型/黄芪桂枝五物汤/贝叶斯Meta分析/疗效/安全性Key words
cervical spondylosis,radiculopathy/Huangqi Guizhi Wuwu decoction/Bayesian meta-analysis/clinical effects/safety分类
医药卫生引用本文复制引用
瞿清辉,许金海,莫文..黄芪桂枝五物汤治疗神经根型颈椎病的贝叶斯Meta分析[J].西部中医药,2026,39(6):49-54,6.基金项目
上海卫生健康委员会海派中医流派传承创新团队(2021LPTD-008) （2021LPTD-008）
中医非药物疗法示范中心建设(ZY[2021-2023]-0204-06). （ZY[2021-2023]-0204-06）
