中国实用神经疾病杂志2026,Vol.29Issue(6):661-666,6.DOI:10.12083/SYSJ.251883
合并亚临床甲状腺功能减退的脑梗死临床特点及影响因素
Clinical characteristics and influencing factors of cerebral infarction complicated with subclinical hypothyroidism
摘要
Abstract
Objective To analyze the clinical characteristics of arteriosclerotic cerebral infarction(ASCI)complicated with subclinical hypothyroidism(SCH),and explore its influencing factors.Methods This retrospective study collected clinical data from ASCI patients admitted to the Department of Neurology,Beijing Tongren Hospital,Capital Medical University between January 1,2020 and August 1,2022.The propensity score matching method was used to analyze the clinical characteristics of ASCI patients complicated with SCH,and univariate and multivariate Logistic regression were applied to explore its influencing factors.Results The SCH group had significantly lower rates of hypertension(74.36%vs 93.91%,P<0.001),hyperlipidemia(15.38%vs 85.28%,P<0.001),and hyperhomocysteinemia(5.13%vs 20.30%,P<0.001)compared to the non-SCH group.C-reactive protein(OR=0.735,95%CI:0.572-0.924,P=0.011),neutrophils(OR=1.964,95%CI:1.263-3.210,P=0.004),hypertension(OR=0.178,95%CI:0.042-0.722,P=0.016),and hyperlipidemia(OR=0.021,95%CI:0.006-0.062,P<0.001)as influencing factors for ASCI complicated with SCH.Conclusion C-reactive protein,neutrophils,hypertension,and hyperlipidemia may be influencing factors for ASCI complicated with SCH.关键词
动脉粥样硬化性脑梗死/亚临床甲状腺功能减退/影响因素/倾向性匹配/C反应蛋白Key words
Arteriosclerotic cerebral infarction/Subclinical hypothyroidism/Influencing factors/Propensity score matching/C-reactive protein分类
医药卫生引用本文复制引用
马中华,江汉秋,王佳伟..合并亚临床甲状腺功能减退的脑梗死临床特点及影响因素[J].中国实用神经疾病杂志,2026,29(6):661-666,6.基金项目
北京同仁医院院内基金项目(编号:TRYY-KYJJ-2017-054) (编号:TRYY-KYJJ-2017-054)