中国实用神经疾病杂志2026，Vol.29Issue(6)：723-727,5.DOI:10.12083/SYSJ.250229
术前C反应蛋白/白蛋白比值对三叉神经痛微血管减压术后切口愈合不良的预测价值
Predictive value of preoperative C-reactive protein/albumin ratio for poor incision healing after microvascular decompression for trigeminal neuralgia
摘要
Abstract
Objective To investigate the predictive value of preoperative C-reactive protein/albumin ratio(CAR)for poor incision healing after microvascular decompression(MVD)for trigeminal neuralgia.Methods The clinical data of 104 patients with trigeminal neuralgia who underwent MVD in the Affiliated Hospital of Xuzhou Medical University from March 2019 to March 2024 were retrospectively analyzed.According to the incision healing status at the surgical site after operation,104 patients with trigeminal neuralgia were divided into the good incision healing group(n=86)and the poor incision healing group(n=18).The preoperative levels of C-reactive protein(CRP)and albumin(ALB)were collected,and CAR was calculated.Receiver operating characteristic(ROC)curve was used to analyze the predictive value of preoperative CAR for poor incision healing after MVD for trigeminal neuralgia,and multivariate Logistic stepwise regression analysis was used to explore the influencing factors of poor incision healing after MVD for trigeminal neuralgia.Results The preoperative CRP and CAR levels in the poor incision healing group were higher than those in the good incision healing group,while the ALB level was lower(P<0.05).ROC curve analysis showed that the area under curve(AUC)of preoperative CAR for predicting poor incision healing after MVD for trigeminal neuralgia was 0.919,which was significantly larger than that of preoperative CRP and ALB alone(0.792 and 0.874,respectively,Z=6.831,9.208,P<0.001).The poor incision healing group had higher age,BMI,proportion of patients with diabetes,proportion of hospital stay≥10 days,proportion of operation time≥3 hours,and proportion of incision length≥8 cm than the good incision healing group(P<0.05).Multivariate Logistic analysis showed that combined diabetes mellitus(OR=2.280,95%CI:1.421-3.656),operation time≥3 hours(OR=2.052,95%CI:1.320-3.190),incision length≥8 cm(OR=2.552,95%CI:1.263-5.158),and preoperative CAR≥0.22(OR=3.184,95%CI:1.744-5.811)were risk factors for poor incision healing after MVD for trigeminal neuralgia(P<0.05).Conclusion High expression of preoperative CAR is an independent risk factor for poor incision healing after MVD for trigeminal neuralgia,and it has good clinical value for predicting poor incision healing after MVD for trigeminal neuralgia.关键词
C反应蛋白/白蛋白比值/三叉神经痛/微血管减压术/切口愈合不良/预测价值Key words
C-reactive protein/albumin ratio/Trigeminal neuralgia/Microvascular decompression/Poor incision healing/Predictive value分类
医药卫生引用本文复制引用
史桃圳,肖维汉,王振,张永康,阴鲁鑫,高文昌..术前C反应蛋白/白蛋白比值对三叉神经痛微血管减压术后切口愈合不良的预测价值[J].中国实用神经疾病杂志,2026,29(6):723-727,5.基金项目
江苏省卫生健康委科研项目(编号:MQ2024025) （编号:MQ2024025）
