中国当代医药2026，Vol.33Issue(11)：93-96,101,5.DOI:10.3969/j.issn.1674-4721.2026.11.18
化浊解毒汤合痛泻要方治疗腹泻型肠易激综合征的疗效观察
Observation on the therapeutic effect of Huazhuo Jiedu Decoction com-bined with Tongxie Yaofang in the treatment of irritable bowel syndrome with diarrhea
摘要
Abstract
Objective To explore the therapeutic effect of Huazhuo Jiedu Decoction combined with Tongxie Yaofang in the treatment of irritable bowel syndrome with diarrhea(IBS-D)of the liver-spleen deficiency type and analyze its potential mechanism.Methods A total of 78 patients with IBS-D admitted to the Department of Spleen and Gastroenterology of the Third Affiliated People's Hospital of Fujian University of Traditional Chinese Medicine from September 2023 to August 2024 were selected as the research subjects,they were divided into the observation group and the control group according to random number table method,with 39 cases in each group.The observation group was given oral administration of Huazhuo Jiedu Decoction combined with Tongxie Yaofang,while the control group was given oral administration of Pinaverium Bromide.The treatment course was 4 weeks for both groups.The scores of traditional Chinese medicine syndrome score,irritable bowel syndrome symptom severity scale(IBS-SSS),Hamilton anxiety scale(HAMA),and irritable bowel syndrome quality of life questionnaire(IBS-QOL)before and after treatment were compared in the two groups.Results The scores of traditional Chinese medicine syndrome score,IBS-SSS,and HAMA in both groups after treatment were lower than those before treatment,and the differences were statistically significant(P＜0.05).The scores of IBS-QOL in both groups after treatment were higher than those before treatment,and the differences were statistically significant(P＜0.05).The scores of traditional Chinese medicine syndrome score,IBS-SSS,and HAMA in the observation group after treatment were lower than those in the control group,and the differences were statistically significant(P＜0.05).The score of IBS-QOL in the observa-tion group after treatment was higher than that in the control group,and the difference was statistically significant(P＜0.05).Conclusion The Huazhuo Jiedu Decoction combined with Tongxie Yaofang can improve the clinical symptoms,quality of life,and negative emotions of patients with IBS-D of the liver-spleen deficiency type.关键词
化浊解毒汤/痛泻要方/腹泻型肠易激综合征Key words
Huazhuo Jiedu Decoction/Tongxie Yaofang/Irritable bowel syndrome with diarrhea分类
医药卫生引用本文复制引用
杨美华,陈文辉..化浊解毒汤合痛泻要方治疗腹泻型肠易激综合征的疗效观察[J].中国当代医药,2026,33(11):93-96,101,5.基金项目
福建省省级临床重点专科建设项目(闽卫医政函[2023]1163号) （闽卫医政函[2023]1163号）
福建中医药大学校管课题临床专项项目(XB2023044) （XB2023044）
福建中医药大学中医药传承工作室建设项目(闽中医[2023]56号). （闽中医[2023]56号）
