临床误诊误治2026，Vol.39Issue(11)：7-12,6.DOI:10.3969/j.issn.1002-3429.2026.11.002
机化性肺炎的临床特点及误诊原因分析
Clinical characteristics and causes of misdiagnosis of organizing pneumonia
刘国田 1张汝姣 1安树昌 1李向利 2逄晓莉 1黄新1
作者信息
- 1. 北京华信医院(清华大学第一附属医院)呼吸与危重症医学科,北京 100016
- 2. 北京华信医院(清华大学第一附属医院)病理科,北京 100016
- 折叠
摘要
Abstract
Objective To investigate the clinical features,causes of misdiagnosis,and preventive strategies of organizing pneumonia(OP).Methods The clinical data of seven patients with pathologically confirmed OP,who were initially misdiagnosed as pulmonary infection at the First Hospital of Tsinghua University from September 2020 to February 2026,were retrospectively analyzed.Results The predominant clinical manifestations included fever,cough,sputum production,and wheezing.All patients were initially diagnosed with pulmonary infection based on clinical symptoms,laboratory tests,and chest imaging,but showed unsatisfactory responses to empirical antimicrobial therapy.Definite diagnoses of OP were subsequently established via bronchoscopic alveolar lavage,transbronchial lung biopsy,or percutaneous lung puncture biopsy.The misdiagnosis duration ranged from 1 week to 4 months.After initiation of glucocorticoid therapy,all patients achieved clinical remission with favorable outcomes during follow-up.Conclusion OP is frequently misdiagnosed owing to its atypical and heterogeneous early presentations.Enhanced clinical vigilance,detailed history taking,targeted laboratory evaluation,and appropriate invasive examinations are essential to reduce or avoid misdiagnosis.关键词
机化性肺炎/误诊/肺部感染/糖皮质激素/支气管镜检查/肺穿刺/鉴别诊断Key words
organizing pneumonia/misdiagnosis/pulmonary infection/glucocorticoid/bronchoscopy/lung punctures/differential diagnosis引用本文复制引用
刘国田,张汝姣,安树昌,李向利,逄晓莉,黄新..机化性肺炎的临床特点及误诊原因分析[J].临床误诊误治,2026,39(11):7-12,6.
