现代畜牧兽医Issue(5)：23-27,5.DOI:10.20154/j.cnki.issn1672-9692.2026.05.005
忍冬藤提取物体外抑菌、抗病毒效果评价
Evaluation of the in vitro antibacterial and antiviral effects of Lonicera japonica Thunb.stem extract
摘要
Abstract
The aim of this study was to investigate the feasibility of using Lonicera japonica Thunb.stem as a feed material.Its extract was obtained by decoction,and its antibacterial and antiviral effects were evaluated.The results showed that the highest content of chlorogenic acid in the aqueous extract of Lonicera japonica Thunb.stem was 2.852 mg/g.The minimum inhibitory concentration(MIC)and minimum bactericidal concentration(MBC)against Staphylococcus aureus and Escherichia coli were both 500 g/L.The maximum safe concentration for LMH cells was 3.125 g/L.At this concentration,the extract could neither block infection by fowl adenovirus subtype 4(FAdV-4)nor inhibit the proliferation of FAdV-4.After exposure to 6.250 g/L of the extract in vitro,the protection rate for LMH cells was 16.7％,but there was no significant difference in viral titer compared with the control group.The study indicates that the extract of Lonicera japonica Thunb.stem possesses certain antibacterial activity.For antiviral activity assessment,a carrier with stronger biological activity should be screened.关键词
忍冬藤/体外抑菌/抗病毒Key words
Lonicera japonica Thunb.stem/In vitro antibacterial/Antiviral activity分类
农业科技引用本文复制引用
李秀丽,张漫,孙萌,赵云平,赵琳琳,魏静娜,苏蘩,刘征辉..忍冬藤提取物体外抑菌、抗病毒效果评价[J].现代畜牧兽医,2026,(5):23-27,5.基金项目
天津市农业农村委员会产学研用合作"揭榜挂帅"项目(GBGG202302) （GBGG202302）
