山西中医药大学学报2026，Vol.27Issue(5)：514-519,6.DOI:10.19763/j.cnki.2096-7403.2026.02.20
三合宁嗽汤治疗肺脾气虚型肺部术后慢性咳嗽临床观察
Clinical study on Sanhe Ningsou Decoction in treating chronic cough after surgery(lung and spleen qi deficiency pattern)
摘要
Abstract
Objective:To evaluate the clinical efficacy of Sanhe Ningsou Decoction(Three Mixtures Cough-Quieting Decoction)combined with compound methoxyphenamine capsule in treating chronic cough after lung surgery(lung-spleen qi deficiency pattern).Methods:A total of 60 patients with chronic cough after lung surgery(lung-spleen qi deficiency pat-tern)admitted to the First Affiliated Hospital of Anhui University of Chinese Medicine from January to October 2024 were selected and divided into a treatment group(30 cases)and a control group(30 cases).The control group received oral com-pound methoxyphenamine capsule,while the treatment group received oral Sanhe Ningsou Decoction in addition to the con-trol treatment.The composition of Sanhe Ningsou Decoction included Maidong 15 g,Banxia 10 g,Chaihu 10 g,Huangqin 10 g,Renshen 10 g,Jiangcan 9 g,Chantui 9 g,Pianjianghuang 9 g,Chaodahuang 12 g,Shengjiang 10 g,and Dazao 10 g.Both groups were treated for 4 weeks.The main observation indicators included the scores of the Chinese version of the Leicester Cough Questionnaire(LCQ-MC),cough symptom score,and traditional Chinese medicine(TCM)syndrome score before and after treatment,and clinical efficacy was evaluated.Results:After treatment,the physiological,psychological,and social di-mensions and total score of LCQ-MC in both groups were significantly increased compared with before treatment,while the cough symptom score and TCM syndrome score were significantly decreased.The treatment group showed better improve-ments in all indicators than the control group,with statistically significant differences(P<0.05,P<0.01).The total effective rate in the treatment group was significantly higher than that in the control group(73.3%vs.40.0%),and the incidence of adverse reactions was lower in the treatment group,with statistically significant differences(P<0.05).Conclusion:Sanhe Ningsou Decoction combined with compound methoxyphenamine capsule can significantly improve cough symptoms and quality of life in patients with chronic cough after lung surgery(lung-spleen qi deficiency pattern),enhance clinical efficacy,and demonstrate the advantages of integrated Chinese and Western medicine therapy.关键词
肺部手术后/慢性咳嗽/三合宁嗽汤/肺脾气虚证/中西医结合疗法Key words
after lung surgery/chronic cough/Sanhe Ningsou Decoction(Three Mixtures Cough-Quieting Decoc-tion)/lung-spleen qi deficiency pattern/integrated Chinese and Western medicine therapy分类
医药卫生引用本文复制引用
姚星晨,凌逸,刘新如,刘雨晴,刘荣妹,祝永福..三合宁嗽汤治疗肺脾气虚型肺部术后慢性咳嗽临床观察[J].山西中医药大学学报,2026,27(5):514-519,6.基金项目
安徽省教育厅项目(2022AH050415) （2022AH050415）
安徽中医药大学2022年高校科研项目(2022HZ009) （2022HZ009）
