上海预防医学2026，Vol.38Issue(4)：280-283,4.DOI:10.19428/j.cnki.sjpm.2026.250333
中国东部监狱羁押人群结核潜伏感染的流行病学特征及影响因素
Epidemiological characteristics and influencing factors of latent tuberculosis infection among detainees in eastern China
摘要
Abstract
[Objective]To analyze the epidemiological characteristics of latent tuberculosis infection(LTBI)among newly detained populations in eastern China,to identify high-risk groups,and to provide a scientific basis for formulating tuberculosis prevention and control strategies in the prison system.[Methods]A cross-sectional study was conducted among the newly admitted detainees in two prisons in eastern China in 2022.Data on demographic characteristics,behavioral risk factors and previous disease history of the research subjects were collected through a structured questionnaire survey.The LTBI status of the detainees was determined using the QuantiFERON-TB Gold In-Tube(QFT-GIT)method.Lasso regression was used to screen variables,followed by multivariate logistic regression analysis to investigate the influencing factors of LTBI.[Results]A total of 305 detainees were included in the study.The median age of detainees was 35(31,43)years.The study population was predominantly male(67.21%),of Han ethnicity(95.41%),had a junior or senior high school education(59.34%),and was unemployed(31.80%).A history of smoking was reported by 52.79%of participants,while 57.70%reported no alcohol consumption.The majority had no history of hypertension(85.90%),diabetes mellitus(93.77%),human immunodeficiency virus(HIV)infection(97.38%),familial genetic diseases(95.08%),surgery or trauma(73.77%),drug use(92.79%),or hepatitis(93.77%).The LTBI rate was 14.75%.After comparing the demographic characteristics of LTBI and non-infected groups,it was found that smoking history(χ2=7.40,P=0.025),drug use history(χ2=5.49,P=0.019),and HIV infection(χ2=8.12,P=0.004)were statistically correlated with LTBI infection.The results of multivariate logistic regression analyses showed that smoking[adjusted odds ratio(aOR)=4.08,95%CI:1.60-10.42,P=0.003],HIV infection(aOR=11.57,95%CI:2.50-53.51,P=0.002)and drug use(aOR=3.04,95%CI:1.02-9.09,P=0.046)were risk factors for LTBI.[Conclusion]The LTBI rate among newly detainees in two prisons in eastern China is slightly lower than that among long-term detainees.Early screening and intervention should be implemented for newly detainees,with particular attention focused on high-risk groups such as those with a history of smoking,HIV infection,or drug use.关键词
结核分枝杆菌/结核潜伏感染/监狱/羁押人群/影响因素Key words
Mycobacterium tuberculosis/latent tuberculosis infection/prison/detained population/influencing factor分类
医药卫生引用本文复制引用
费心如,卢鹏,宁静娴,潘昱辰,竺丽梅,刘巧,周红喜..中国东部监狱羁押人群结核潜伏感染的流行病学特征及影响因素[J].上海预防医学,2026,38(4):280-283,4.基金项目
国家自然科学基金项目(82003516) （82003516）
江苏省卫生健康委员会科研面上项目(M2020020) （M2020020）
