沈阳医学院学报2026，Vol.28Issue(3)：264-268,5.DOI:10.16753/j.cnki.1008-2344.2026.03.007
右美托咪定作为局麻药佐剂用于超声下髂筋膜间隙阻滞在老年股骨骨折应用研究
Dexmedetomidine as a local anesthetic adjuvant in ultrasound-guided fascia iliaca compartment block for elderly patients with femoral fractures
摘要
Abstract
Objective:To investigate the effect of dexmedetomidine(DEX)as a local anesthetic adjuvant in ultrasound-guided fascia iliaca compartment block(FICB)in elderly patients with femoral fractures.Methods:Sixty elderly patients with femoral fractures admitted to Dongxiang District People's Hospital of Fuzhou City from Mar 2024 to Jun 2025 were selected and randomly divided into an observation group and a control group,with 30 cases in each group.The control group received ropivacaine under ultrasound-guided FICB,while the observation group received DEX combined with ropivacaine under ultrasound-guided FICB.Hemodynamic indicators[mean arterial pressure and heart rate at T0(after entering the operating room),T1(10 min after nerve block),T2(when the lateral position was placed),and T3(at the end of the operation)],postoperative pain degree[assessed by visual analogue scale(VAS)],anesthetic efficacy,frequency of vasoactive drug use,and recovery time were compared between the two groups.Results:There was no statistically significant difference in surgical time between the two groups(P＞0.05).Mean arterial pressure and heart rate at T0-T3 showed no statistically significant difference in the observation groups(P＞0.05).In the control group,mean arterial pressure and heart rate at T1-T3 were lower than those at T0 and were also lower than those in the observation group(P＜0.05).VAS scores at 6,12,24,and 48 h postoperatively in the observation group were lower than those in the control group(P＜0.05).The onset time of blockade was shorter while the duration of blockade was longer in the observation group than those in the control group(P＜0.05).The number of vasoactive drug administrations was lower in the observation group than that in the control group(P＜0.05).There was no statistically significant difference between the two groups in the time to first ambulation or total hospitalization duration(P＞0.05).Conclusion:The use of DEX as a local anesthetic adjuvant in ultrasound-guided FICB for elderly patients with femoral fractures can stabilize hemodynamics,reduce postoperative pain,improve anesthetic efficacy,reduce the use of vasoactive drugs,and has no effect on recovery indicators.关键词
股骨骨折/老年/右美托咪定/超声下髂筋膜间隙阻滞Key words
femoral fractures/elderly patients/dexmedetomidine/ultrasound-guided fascia iliaca compartment block分类
医药卫生引用本文复制引用
胡琛,于江秀,董晨晨..右美托咪定作为局麻药佐剂用于超声下髂筋膜间隙阻滞在老年股骨骨折应用研究[J].沈阳医学院学报,2026,28(3):264-268,5.基金项目
抚州市社会发展指导性科技计划项目(No.抚科社学[2024]6号-121) （No.抚科社学[2024]6号-121）
