现代妇产科进展2026，Vol.35Issue(5)：357-362,6.DOI:10.13283/j.cnki.xdfckjz.2026.05.035
全身炎症指标对子宫颈环扎术后妊娠结局预测价值的研究
Study on the predictive value of systemic inflammatory markers for pregnancy outcomes after cervical cerclage
摘要
Abstract
Objective:To explore the predictive value of preoperative systemic inflam-matory markers for pregnancy outcomes after cervical cerclage.Methods:A total of 124 single-ton pregnant women who underwent cervical cerclage and delivered in our hospital from January 1,2022 to October 30,2025 were selected and divided into three groups according to the indica-tions for cerclage:35 cases in the history-indicated group,66 cases in the ultrasound-indicated group,and 23 cases in the physical examination-indicated group.Inflammatory markers(SⅡ,SIRI,NMR,PLR,NLR,MLR)were calculated based on the peripheral blood of pregnant women.The distribution of these markers among the three groups with different cerclage indica-tions was compared.The relationship between inflammatory markers and pregnancy outcomes was evaluated by correlation analysis,and for the inflammatory markers with significant correla-tion,ROC curve analysis was further used to assess their predictive value.Results:Among the three groups with different cerclage indications,there were significant differences in SⅡ,SIRI,PLR,NLR and MLR(P<0.05).The above indicators in the physical examination-indicated group were significantly higher than those in the other two groups.The cerclage failure rate and the delivery rate before 34 weeks of gestation in this group were significantly higher than those in the other two groups(P<0.05),while the neonatal birth weight and 1-minute Apgar score were significantly lower,the NICU admission rate was significantly higher,and the interval from cerclage to delivery was the shortest.Correlation analysis showed that SⅡ,SIRI and NLR were significantly negatively correlated with gestational age at delivery,neonatal birth weight,1-mi-nute Apgar score and interval from cerclage to delivery(P<0.05).ROC curve analysis indica-ted that SⅡ,SIRI and NLR had statistically significant predictive value for delivery before 34 weeks of gestation and neonatal low birth weight(P<0.05).Conclusion:The levels of SⅡ,SI-RI and NLR are important biochemical markers for predicting the outcome of cervical cerclage and pregnancy outcomes.They can be used as non-invasive predictive indicators in preoperative assessment to assist clinical risk stratification.关键词
全身炎症指标/宫颈环扎术/妊娠结局Key words
Systemic inflammatory markers/Cervical cerclage/Pregnancy outcomes分类
医药卫生引用本文复制引用
刘影诺,王永萍,朱丽业,蒋红清..全身炎症指标对子宫颈环扎术后妊娠结局预测价值的研究[J].现代妇产科进展,2026,35(5):357-362,6.基金项目
北京市海淀区属卫生健康系统高层次人才计划发展项目(北京市卫生局重点学科基金)(No:2022HDXD006) （北京市卫生局重点学科基金）
